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Streamlined process for the chemical synthesis of RNA using 2'-O-thionocarbamate-protected nucleoside phosphoramidites in the solid phase.
J Am Chem Soc. 2011 Aug 3;133(30):11540-56. doi: 10.1021/ja201561z. Epub 2011 Jul 11.
J Am Chem Soc. 2011.
PMID: 21688829
Solid-phase oligodeoxynucleotide synthesis: a two-step cycle using peroxy anion deprotection.
Sierzchala AB, Dellinger DJ, Betley JR, Wyrzykiewicz TK, Yamada CM, Caruthers MH.
Sierzchala AB, et al.
J Am Chem Soc. 2003 Nov 5;125(44):13427-41. doi: 10.1021/ja030376n.
J Am Chem Soc. 2003.
PMID: 14583038
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Synthesis of mixed sequence borane phosphonate DNA.
McCuen HB, Noé MS, Sierzchala AB, Higson AP, Caruthers MH.
McCuen HB, et al. Among authors: sierzchala ab.
J Am Chem Soc. 2006 Jun 28;128(25):8138-9. doi: 10.1021/ja061757e.
J Am Chem Soc. 2006.
PMID: 16787069
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The synthesis of dithymidine boranophosphate by the oxathiaphospholane approach.
Okruszek A, Sierzchała A, Zmudzka K, Stec WJ.
Okruszek A, et al.
Nucleosides Nucleotides Nucleic Acids. 2001 Oct-Nov;20(10-11):1843-9. doi: 10.1081/NCN-100107195.
Nucleosides Nucleotides Nucleic Acids. 2001.
PMID: 11719997
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Oxathiaphospholane Method of Stereocontrolled Synthesis of Diribonucleoside 3',5'-Phosphorothioates.
Sierzchala A, Okruszek A, Stec WJ.
Sierzchala A, et al.
J Org Chem. 1996 Sep 20;61(19):6713-6716. doi: 10.1021/jo960811e.
J Org Chem. 1996.
PMID: 11667545
No abstract available.
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The First Stereocontrolled Solid-Phase Synthesis of Di-, Tri-, and Tetra[adenosine (2',5') phosphorothioate]s.
Yang XB, Sierzchala A, Misiura K, Niewiarowski W, Sochacki M, Stec WJ, Wieczorek MW.
Yang XB, et al.
J Org Chem. 1998 Oct 2;63(20):7097-7100. doi: 10.1021/jo980522l.
J Org Chem. 1998.
PMID: 11672339
No abstract available.
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Structural effect of complete [Rp]-phosphorothioate and phosphorodithioate substitutions in the DNA strand of a model antisense inhibitor-target RNA complex.
Furrer P, Billeci TM, Donati A, Kojima C, Karwowski B, Sierzchala A, Stec W, James TL.
Furrer P, et al.
J Mol Biol. 1999 Jan 29;285(4):1609-22. doi: 10.1006/jmbi.1998.2305.
J Mol Biol. 1999.
PMID: 9917400
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