Holst PJ - Search Results

1

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.

Benned-Jensen T, Smethurst C, Holst PJ, Page KR, Sauls H, Sivertsen B, Schwartz TW, Blanchard A, Jepras R, Rosenkilde MM. Benned-Jensen T, et al. Among authors: holst pj. J Biol Chem. 2011 Aug 19;286(33):29292-29302. doi: 10.1074/jbc.M110.196345. Epub 2011 Jun 14. J Biol Chem. 2011. PMID: 21673108 Free PMC article.

2

Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74.

Rosenkilde MM, Kledal TN, Holst PJ, Schwartz TW. Rosenkilde MM, et al. Among authors: holst pj. J Biol Chem. 2000 Aug 25;275(34):26309-15. doi: 10.1074/jbc.M003800200. J Biol Chem. 2000. PMID: 10842179 Free article.

3

Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.

Holst PJ, Rosenkilde MM, Manfra D, Chen SC, Wiekowski MT, Holst B, Cifire F, Lipp M, Schwartz TW, Lira SA. Holst PJ, et al. Among authors: holst b. J Clin Invest. 2001 Dec;108(12):1789-96. doi: 10.1172/JCI13622. J Clin Invest. 2001. PMID: 11748262 Free PMC article.

4

Virally encoded chemokines and chemokine receptors in the role of viral infections.

Holst PJ, Lüttichau HR, Schwartz TW, Rosenkilde MM. Holst PJ, et al. Contrib Microbiol. 2003;10:232-52. doi: 10.1159/000068138. Contrib Microbiol. 2003. PMID: 12530329 Review.

5

Microbiological exploitation of the chemokine system.

Holst PJ, Rosenkilde MM. Holst PJ, et al. Microbes Infect. 2003 Feb;5(2):179-87. doi: 10.1016/s1286-4579(02)00081-3. Microbes Infect. 2003. PMID: 12650776 Free article. Review.

6

The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins.

Rosenkilde MM, McLean KA, Holst PJ, Schwartz TW. Rosenkilde MM, et al. Among authors: holst pj. J Biol Chem. 2004 Jul 30;279(31):32524-33. doi: 10.1074/jbc.M313392200. Epub 2004 May 20. J Biol Chem. 2004. PMID: 15155729 Free article.

7

McLean KA, Holst PJ, Martini L, Schwartz TW, Rosenkilde MM. McLean KA, et al. Among authors: holst pj. Virology. 2004 Aug 1;325(2):241-51. doi: 10.1016/j.virol.2004.04.027. Virology. 2004. PMID: 15246264 Free article.

8

Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.

Ugleholdt R, Poulsen ML, Holst PJ, Irminger JC, Orskov C, Pedersen J, Rosenkilde MM, Zhu X, Steiner DF, Holst JJ. Ugleholdt R, et al. Among authors: holst pj, holst jj. J Biol Chem. 2006 Apr 21;281(16):11050-7. doi: 10.1074/jbc.M601203200. Epub 2006 Feb 13. J Biol Chem. 2006. PMID: 16476726 Free article.

9

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.

Rosenkilde MM, Benned-Jensen T, Andersen H, Holst PJ, Kledal TN, Lüttichau HR, Larsen JK, Christensen JP, Schwartz TW. Rosenkilde MM, et al. Among authors: holst pj. J Biol Chem. 2006 May 12;281(19):13199-13208. doi: 10.1074/jbc.M602245200. Epub 2006 Mar 15. J Biol Chem. 2006. PMID: 16540462 Free article.

10

Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain.

Ugleholdt R, Pedersen J, Bassi MR, Füchtbauer EM, Jørgensen SM, Kissow HL, Nytofte N, Poulsen SS, Rosenkilde MM, Seino Y, Thams P, Holst PJ, Holst JJ. Ugleholdt R, et al. Among authors: holst pj, holst jj. J Biol Chem. 2011 Dec 30;286(52):44632-45. doi: 10.1074/jbc.M111.311779. Epub 2011 Oct 25. J Biol Chem. 2011. PMID: 22027838 Free PMC article.

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