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The molecular basis of glyphosate resistance by an optimized microbial acetyltransferase.
Siehl DL, Castle LA, Gorton R, Keenan RJ. Siehl DL, et al. J Biol Chem. 2007 Apr 13;282(15):11446-55. doi: 10.1074/jbc.M610267200. Epub 2007 Feb 1. J Biol Chem. 2007. PMID: 17272278 Free article.
GAT is an N-acetyltransferase from Bacillus licheniformis that was optimized by gene shuffling for acetylation of the broad spectrum herbicide, glyphosate, forming the basis of a novel mechanism of glyphosate tolerance in transgenic plants (Castle, L. A., Siehl, D. …
GAT is an N-acetyltransferase from Bacillus licheniformis that was optimized by gene shuffling for acetylation of the broad spectrum herbici …
History and Outlook for Glyphosate-Resistant Crops.
Green JM, Siehl DL. Green JM, et al. Among authors: siehl dl. Rev Environ Contam Toxicol. 2021;255:67-91. doi: 10.1007/398_2020_54. Rev Environ Contam Toxicol. 2021. PMID: 34109481
Discovery and directed evolution of a glyphosate tolerance gene.
Castle LA, Siehl DL, Gorton R, Patten PA, Chen YH, Bertain S, Cho HJ, Duck N, Wong J, Liu D, Lassner MW. Castle LA, et al. Among authors: siehl dl. Science. 2004 May 21;304(5674):1151-4. doi: 10.1126/science.1096770. Science. 2004. PMID: 15155947
Broad 4-hydroxyphenylpyruvate dioxygenase inhibitor herbicide tolerance in soybean with an optimized enzyme and expression cassette.
Siehl DL, Tao Y, Albert H, Dong Y, Heckert M, Madrigal A, Lincoln-Cabatu B, Lu J, Fenwick T, Bermudez E, Sandoval M, Horn C, Green JM, Hale T, Pagano P, Clark J, Udranszky IA, Rizzo N, Bourett T, Howard RJ, Johnson DH, Vogt M, Akinsola G, Castle LA. Siehl DL, et al. Plant Physiol. 2014 Nov;166(3):1162-76. doi: 10.1104/pp.114.247205. Epub 2014 Sep 5. Plant Physiol. 2014. PMID: 25192697 Free PMC article.
63 results