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Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism.
Lind S, Holdfeldt A, Mårtensson J, Sundqvist M, Björkman L, Forsman H, Dahlgren C. Lind S, et al. Among authors: martensson j. FASEB J. 2019 Jun;33(6):6887-6903. doi: 10.1096/fj.201802309R. Epub 2019 Feb 26. FASEB J. 2019. PMID: 30808243
Further, the finding that an allosteric FFA2R modulator sensitizes not only the response induced by orthosteric FFA2R agonists, but also the response induced by ATP (P2Y(2)R-specific agonist) and formyl peptide receptor-specific agonists, violates the receptor restriction charact …
Further, the finding that an allosteric FFA2R modulator sensitizes not only the response induced by orthosteric FFA2R agonists, but also the …
The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment.
Björkman L, Mårtensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, Bylund J, Højgaard Hansen A, Pandey SK, Ulven T, Forsman H, Dahlgren C. Björkman L, et al. Among authors: martensson j. Mol Cell Biol. 2016 Sep 26;36(20):2583-95. doi: 10.1128/MCB.00161-16. Print 2016 Oct 15. Mol Cell Biol. 2016. PMID: 27503855 Free PMC article.
441 results