Kumar A - Search Results

1

Water-mediated binding of agents that target the DNA minor groove.

Liu Y, Kumar A, Depauw S, Nhili R, David-Cordonnier MH, Lee MP, Ismail MA, Farahat AA, Say M, Chackal-Catoen S, Batista-Parra A, Neidle S, Boykin DW, Wilson WD. Liu Y, et al. Among authors: kumar a. J Am Chem Soc. 2011 Jul 6;133(26):10171-83. doi: 10.1021/ja202006u. Epub 2011 Jun 15. J Am Chem Soc. 2011. PMID: 21627167 Free PMC article.

2

Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine.

Nguyen B, Tardy C, Bailly C, Colson P, Houssier C, Kumar A, Boykin DW, Wilson WD. Nguyen B, et al. Among authors: kumar a. Biopolymers. 2002 Apr 15;63(5):281-97. doi: 10.1002/bip.10073. Biopolymers. 2002. PMID: 11877739

3

Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove.

Wang L, Kumar A, Boykin DW, Bailly C, Wilson WD. Wang L, et al. Among authors: kumar a. J Mol Biol. 2002 Mar 29;317(3):361-74. doi: 10.1006/jmbi.2002.5433. J Mol Biol. 2002. PMID: 11922670

4

Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.

Lansiaux A, Dassonneville L, Facompré M, Kumar A, Stephens CE, Bajic M, Tanious F, Wilson WD, Boykin DW, Bailly C. Lansiaux A, et al. Among authors: kumar a. J Med Chem. 2002 May 9;45(10):1994-2002. doi: 10.1021/jm010539n. J Med Chem. 2002. PMID: 11985467

5

Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.

Lansiaux A, Tanious F, Mishal Z, Dassonneville L, Kumar A, Stephens CE, Hu Q, Wilson WD, Boykin DW, Bailly C. Lansiaux A, et al. Among authors: kumar a. Cancer Res. 2002 Dec 15;62(24):7219-29. Cancer Res. 2002. PMID: 12499262

6

Cooperative dimerization of a heterocyclic diamidine determines sequence-specific DNA recognition.

Tanious F, Wilson WD, Wang L, Kumar A, Boykin DW, Marty C, Baldeyrou B, Bailly C. Tanious F, et al. Among authors: kumar a. Biochemistry. 2003 Nov 25;42(46):13576-86. doi: 10.1021/bi034852y. Biochemistry. 2003. PMID: 14622004

7

Activities of dicationic compounds against Trichomonas vaginalis.

Crowell AL, Stephens CE, Kumar A, Boykin DW, Secor WE. Crowell AL, et al. Among authors: kumar a. Antimicrob Agents Chemother. 2004 Sep;48(9):3602-5. doi: 10.1128/AAC.48.9.3602-3605.2004. Antimicrob Agents Chemother. 2004. PMID: 15328138 Free PMC article.

8

Thiophene-based diamidine forms a "super" at binding minor groove agent.

Mallena S, Lee MP, Bailly C, Neidle S, Kumar A, Boykin DW, Wilson WD. Mallena S, et al. Among authors: kumar a. J Am Chem Soc. 2004 Oct 27;126(42):13659-69. doi: 10.1021/ja048175m. J Am Chem Soc. 2004. PMID: 15493923

9

Structural selectivity of aromatic diamidines.

Chaires JB, Ren J, Hamelberg D, Kumar A, Pandya V, Boykin DW, Wilson WD. Chaires JB, et al. Among authors: kumar a. J Med Chem. 2004 Nov 4;47(23):5729-42. doi: 10.1021/jm049491e. J Med Chem. 2004. PMID: 15509172

10

Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo.

de Souza EM, Oliveira GM, Boykin DW, Kumar A, Hu Q, De Nazaré C Soeiro M. de Souza EM, et al. Among authors: kumar a. J Antimicrob Chemother. 2006 Sep;58(3):610-4. doi: 10.1093/jac/dkl259. Epub 2006 Jul 19. J Antimicrob Chemother. 2006. PMID: 16854954

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