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The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids.
Kamlekar RK, Simanshu DK, Gao YG, Kenoth R, Pike HM, Prendergast FG, Malinina L, Molotkovsky JG, Venyaminov SY, Patel DJ, Brown RE. Kamlekar RK, et al. Biochim Biophys Acta. 2013 Feb;1831(2):417-27. doi: 10.1016/j.bbalip.2012.10.010. Epub 2012 Nov 16. Biochim Biophys Acta. 2013. PMID: 23159414 Free PMC article.
Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.
Ochoa-Lizarralde B, Gao YG, Popov AN, Samygina VR, Zhai X, Mishra SK, Boldyrev IA, Molotkovsky JG, Simanshu DK, Patel DJ, Brown RE, Malinina L. Ochoa-Lizarralde B, et al. J Biol Chem. 2018 Oct 26;293(43):16709-16723. doi: 10.1074/jbc.RA117.000733. Epub 2018 Sep 11. J Biol Chem. 2018. PMID: 30206120 Free PMC article.
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