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Page 1
(S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist.
Poulie CBM, Larsen Y, Leteneur C, Barthet G, Bjørn-Yoshimoto WE, Malhaire F, Nielsen B, Pin JP, Mulle C, Pickering DS, Bunch L. Poulie CBM, et al. Among authors: larsen y. ACS Chem Neurosci. 2022 May 18;13(10):1580-1587. doi: 10.1021/acschemneuro.2c00162. Epub 2022 Apr 27. ACS Chem Neurosci. 2022. PMID: 35475632
Stereoselective Synthesis of New (2S,3R)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp3)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors.
Kayser S, Hansen JC, Staudt M, Moroz A, Larsen Y, Temperini P, Yi F, Syrenne JT, Krogsgaard-Larsen N, Iliadis S, Nielsen B, Hansen KB, Pickering DS, Bunch L. Kayser S, et al. Among authors: larsen y. ACS Chem Neurosci. 2020 Mar 4;11(5):674-701. doi: 10.1021/acschemneuro.0c00003. Epub 2020 Feb 17. ACS Chem Neurosci. 2020. PMID: 32065744 Free PMC article.
Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters.
Poulie CBM, Alcaide A, Krell-Jørgensen M, Larsen Y, Astier E, Bjørn-Yoshimoto WE, Yi F, Syrenne JT, Storgaard M, Nielsen B, Frydenvang KA, Jensen AA, Hansen KB, Pickering DS, Bunch L. Poulie CBM, et al. Among authors: larsen y. ACS Chem Neurosci. 2019 Jun 19;10(6):2989-3007. doi: 10.1021/acschemneuro.9b00205. Epub 2019 May 24. ACS Chem Neurosci. 2019. PMID: 31124660 Free PMC article.
Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist.
Gynther M, Proietti Silvestri I, Hansen JC, Hansen KB, Malm T, Ishchenko Y, Larsen Y, Han L, Kayser S, Auriola S, Petsalo A, Nielsen B, Pickering DS, Bunch L. Gynther M, et al. Among authors: larsen y. J Med Chem. 2017 Dec 14;60(23):9885-9904. doi: 10.1021/acs.jmedchem.7b01624. Epub 2017 Dec 5. J Med Chem. 2017. PMID: 29205034 Free PMC article.
Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues.
Wang SY, Larsen Y, Navarrete CV, Jensen AA, Nielsen B, Al-Musaed A, Frydenvang K, Kastrup JS, Pickering DS, Clausen RP. Wang SY, et al. Among authors: larsen y. J Med Chem. 2016 Mar 10;59(5):2244-54. doi: 10.1021/acs.jmedchem.5b01982. Epub 2016 Feb 22. J Med Chem. 2016. PMID: 26862980
Covalent structure of soybean seed coat peroxidase.
Welinder KG, Larsen YB. Welinder KG, et al. Among authors: larsen yb. Biochim Biophys Acta. 2004 Apr 8;1698(1):121-6. doi: 10.1016/j.bbapap.2003.11.005. Biochim Biophys Acta. 2004. PMID: 15063322