Karam R - Search Results

1

Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.

Bruno IG, Karam R, Huang L, Bhardwaj A, Lou CH, Shum EY, Song HW, Corbett MA, Gifford WD, Gecz J, Pfaff SL, Wilkinson MF. Bruno IG, et al. Among authors: karam r. Mol Cell. 2011 May 20;42(4):500-10. doi: 10.1016/j.molcel.2011.04.018. Mol Cell. 2011. PMID: 21596314 Free PMC article.

2

The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers.

Karam R, Carvalho J, Bruno I, Graziadio C, Senz J, Huntsman D, Carneiro F, Seruca R, Wilkinson MF, Oliveira C. Karam R, et al. Oncogene. 2008 Jul 10;27(30):4255-60. doi: 10.1038/onc.2008.62. Epub 2008 Apr 21. Oncogene. 2008. PMID: 18427545

3

RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

Huang L, Lou CH, Chan W, Shum EY, Shao A, Stone E, Karam R, Song HW, Wilkinson MF. Huang L, et al. Among authors: karam r. Mol Cell. 2011 Sep 16;43(6):950-61. doi: 10.1016/j.molcel.2011.06.031. Mol Cell. 2011. PMID: 21925383 Free PMC article.

4

A conserved microRNA/NMD regulatory circuit controls gene expression.

Karam R, Wilkinson M. Karam R, et al. RNA Biol. 2012 Jan;9(1):22-6. doi: 10.4161/rna.9.1.18010. Epub 2012 Jan 1. RNA Biol. 2012. PMID: 22258150 Free PMC article.

5

Regulation of nonsense-mediated mRNA decay: implications for physiology and disease.

Karam R, Wengrod J, Gardner LB, Wilkinson MF. Karam R, et al. Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):624-33. doi: 10.1016/j.bbagrm.2013.03.002. Epub 2013 Mar 13. Biochim Biophys Acta. 2013. PMID: 23500037 Free PMC article.

6

Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway.

Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF. Lou CH, et al. Among authors: karam r. Cell Rep. 2014 Feb 27;6(4):748-64. doi: 10.1016/j.celrep.2014.01.028. Epub 2014 Feb 13. Cell Rep. 2014. PMID: 24529710 Free PMC article.

7

The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma.

Liu C, Karam R, Zhou Y, Su F, Ji Y, Li G, Xu G, Lu L, Wang C, Song M, Zhu J, Wang Y, Zhao Y, Foo WC, Zuo M, Valasek MA, Javle M, Wilkinson MF, Lu Y. Liu C, et al. Among authors: karam r. Nat Med. 2014 Jun;20(6):596-8. doi: 10.1038/nm.3548. Epub 2014 May 25. Nat Med. 2014. PMID: 24859531 Free PMC article.

8

The unfolded protein response is shaped by the NMD pathway.

Karam R, Lou CH, Kroeger H, Huang L, Lin JH, Wilkinson MF. Karam R, et al. EMBO Rep. 2015 May;16(5):599-609. doi: 10.15252/embr.201439696. Epub 2015 Mar 25. EMBO Rep. 2015. PMID: 25807986 Free PMC article.

9

Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer.

Frebourg T, Oliveira C, Hochain P, Karam R, Manouvrier S, Graziadio C, Vekemans M, Hartmann A, Baert-Desurmont S, Alexandre C, Lejeune Dumoulin S, Marroni C, Martin C, Castedo S, Lovett M, Winston J, Machado JC, Attié T, Jabs EW, Cai J, Pellerin P, Triboulet JP, Scotte M, Le Pessot F, Hedouin A, Carneiro F, Blayau M, Seruca R. Frebourg T, et al. Among authors: karam r. J Med Genet. 2006 Feb;43(2):138-42. doi: 10.1136/jmg.2005.031385. Epub 2005 Apr 14. J Med Genet. 2006. PMID: 15831593 Free PMC article.

10

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

Oliveira C, Sousa S, Pinheiro H, Karam R, Bordeira-Carriço R, Senz J, Kaurah P, Carvalho J, Pereira R, Gusmão L, Wen X, Cipriano MA, Yokota J, Carneiro F, Huntsman D, Seruca R. Oliveira C, et al. Among authors: karam r. Gastroenterology. 2009 Jun;136(7):2137-48. doi: 10.1053/j.gastro.2009.02.065. Epub 2009 Mar 6. Gastroenterology. 2009. PMID: 19269290

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