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Novel Nrf2/ARE activator, trans-Coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38α/MAPKAPK-2 and PK-N3 signaling pathway.
Chen HH, Wang TC, Lee YC, Shen PT, Chang JY, Yeh TK, Huang CH, Chang HH, Cheng SY, Lin CY, Shih C, Chen CT, Liu WM, Chen CH, Kuo CC. Chen HH, et al. Among authors: chen ct, chen ch. Chem Res Toxicol. 2015 Sep 21;28(9):1681-92. doi: 10.1021/acs.chemrestox.5b00085. Epub 2015 Aug 24. Chem Res Toxicol. 2015. PMID: 26275128
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation.
Tang YC, Hsiao JR, Jiang SS, Chang JY, Chu PY, Liu KJ, Fang HL, Lin LM, Chen HH, Huang YW, Chen YT, Tsai FY, Lin SF, Chuang YJ, Kuo CC. Tang YC, et al. Among authors: chen hh, chen yt. Theranostics. 2021 Mar 11;11(11):5232-5247. doi: 10.7150/thno.53417. eCollection 2021. Theranostics. 2021. PMID: 33859744 Free PMC article.
Investigations of survivin: the past, present and future.
Cheung CH, Cheng L, Chang KY, Chen HH, Chang JY. Cheung CH, et al. Among authors: chen hh. Front Biosci (Landmark Ed). 2011 Jan 1;16(3):952-61. doi: 10.2741/3728. Front Biosci (Landmark Ed). 2011. PMID: 21196211 Free article. Review.
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells.
Chen HH, Chang HH, Chang JY, Tang YC, Cheng YC, Lin LM, Cheng SY, Huang CH, Sun MW, Chen CT, Kuo CC. Chen HH, et al. Among authors: chen ct. Free Radic Biol Med. 2017 Dec;113:505-518. doi: 10.1016/j.freeradbiomed.2017.10.375. Epub 2017 Nov 5. Free Radic Biol Med. 2017. PMID: 29080842
2,916 results