Chen C - Search Results

1

Single-molecule fluorescence measurements of ribosomal translocation dynamics.

Chen C, Stevens B, Kaur J, Cabral D, Liu H, Wang Y, Zhang H, Rosenblum G, Smilansky Z, Goldman YE, Cooperman BS. Chen C, et al. Mol Cell. 2011 May 6;42(3):367-77. doi: 10.1016/j.molcel.2011.03.024. Mol Cell. 2011. PMID: 21549313 Free PMC article.

2

Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots.

Wu B, Zhang H, Sun R, Peng S, Cooperman BS, Goldman YE, Chen C. Wu B, et al. Among authors: chen c. Nucleic Acids Res. 2018 Oct 12;46(18):9736-9748. doi: 10.1093/nar/gky636. Nucleic Acids Res. 2018. PMID: 30011005 Free PMC article.

3

Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome.

Kavaliauskas D, Chen C, Liu W, Cooperman BS, Goldman YE, Knudsen CR. Kavaliauskas D, et al. Among authors: chen c. Nucleic Acids Res. 2018 Sep 19;46(16):8651-8661. doi: 10.1093/nar/gky651. Nucleic Acids Res. 2018. PMID: 30107527 Free PMC article.

4

The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis.

Liu H, Chen C, Zhang H, Kaur J, Goldman YE, Cooperman BS. Liu H, et al. Among authors: chen c. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16223-8. doi: 10.1073/pnas.1103820108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930951 Free PMC article.

5

Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis.

Chen C, Stevens B, Kaur J, Smilansky Z, Cooperman BS, Goldman YE. Chen C, et al. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):16980-5. doi: 10.1073/pnas.1106999108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969541 Free PMC article.

6

FRET-based identification of mRNAs undergoing translation.

Stevens B, Chen C, Farrell I, Zhang H, Kaur J, Broitman SL, Smilansky Z, Cooperman BS, Goldman YE. Stevens B, et al. Among authors: chen c. PLoS One. 2012;7(5):e38344. doi: 10.1371/journal.pone.0038344. Epub 2012 May 31. PLoS One. 2012. PMID: 22693619 Free PMC article.

7

Dynamics of translation by single ribosomes through mRNA secondary structures.

Chen C, Zhang H, Broitman SL, Reiche M, Farrell I, Cooperman BS, Goldman YE. Chen C, et al. Nat Struct Mol Biol. 2013 May;20(5):582-8. doi: 10.1038/nsmb.2544. Epub 2013 Mar 31. Nat Struct Mol Biol. 2013. PMID: 23542154 Free PMC article.

8

Quantifying elongation rhythm during full-length protein synthesis.

Rosenblum G, Chen C, Kaur J, Cui X, Zhang H, Asahara H, Chong S, Smilansky Z, Goldman YE, Cooperman BS. Rosenblum G, et al. Among authors: chen c. J Am Chem Soc. 2013 Jul 31;135(30):11322-9. doi: 10.1021/ja405205c. Epub 2013 Jul 16. J Am Chem Soc. 2013. PMID: 23822614 Free PMC article.

9

EF-Tu dynamics during pre-translocation complex formation: EF-Tu·GDP exits the ribosome via two different pathways.

Liu W, Chen C, Kavaliauskas D, Knudsen CR, Goldman YE, Cooperman BS. Liu W, et al. Among authors: chen c. Nucleic Acids Res. 2015 Oct 30;43(19):9519-28. doi: 10.1093/nar/gkv856. Epub 2015 Sep 3. Nucleic Acids Res. 2015. PMID: 26338772 Free PMC article.

10

Elongation factor G initiates translocation through a power stroke.

Chen C, Cui X, Beausang JF, Zhang H, Farrell I, Cooperman BS, Goldman YE. Chen C, et al. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7515-20. doi: 10.1073/pnas.1602668113. Epub 2016 Jun 16. Proc Natl Acad Sci U S A. 2016. PMID: 27313204 Free PMC article.

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