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Page 1
European regulation on orphan medicinal products: 10 years of experience and future perspectives.
Committee for Orphan Medicinal Products and the European Medicines; Westermark K, Holm BB, Söderholm M, Llinares-Garcia J, Rivière F, Aarum S, Butlen-Ducuing F, Tsigkos S, Wilk-Kachlicka A, N'Diamoi C, Borvendég J, Lyons D, Sepodes B, Bloechl-Daum B, Lhoir A, Todorova M, Kkolos I, Kubáčková K, Bosch-Traberg H, Tillmann V, Saano V, Héron E, Elbers R, Siouti M, Eggenhofer J, Salmon P, Clementi M, Krieviņš D, Matulevičiene A, Metz H, Vincenti AC, Voordouw A, Dembowska-Bagińska B, Nunes AC, Saleh FM, Foltánová T, Možina M, Torrent i Farnell J, Beerman B, Mariz S, Evers MP, Greene L, Thorsteinsson S, Gramstad L, Mavris M, Bignami F, Lorence A, Belorgey C. Committee for Orphan Medicinal Products and the European Medicines, et al. Among authors: lhoir a. Nat Rev Drug Discov. 2011 May;10(5):341-9. doi: 10.1038/nrd3445. Nat Rev Drug Discov. 2011. PMID: 21532564 Review.
Use of biomarkers in the context of orphan medicines designation in the European Union.
Tsigkos S, Llinares J, Mariz S, Aarum S, Fregonese L, Dembowska-Baginska B, Elbers R, Evers P, Foltanova T, Lhoir A, Corrêa-Nunes A, O'Connor D, Voordouw A, Westermark K, Sepodes B. Tsigkos S, et al. Among authors: lhoir a. Orphanet J Rare Dis. 2014 Jan 27;9:13. doi: 10.1186/1750-1172-9-13. Orphanet J Rare Dis. 2014. PMID: 24461084 Free PMC article.
Regulatory watch: The orphan drug pipeline in Europe.
Morel T, Lhoir A, Picavet E, Mariz S, Sepodes B, Llinares J, Cassiman D. Morel T, et al. Among authors: lhoir a. Nat Rev Drug Discov. 2016 Jun 1;15(6):376. doi: 10.1038/nrd.2016.96. Nat Rev Drug Discov. 2016. PMID: 27245390 No abstract available.
Fission time measurements: a new probe into superheavy element stability.
Morjean M, Jacquet D, Charvet JL, L'Hoir A, Laget M, Parlog M, Chbihi A, Chevallier M, Cohen C, Dauvergne D, Dayras R, Drouart A, Escano-Rodriguez C, Frankland JD, Kirsch R, Lautesse P, Nalpas L, Ray C, Schmitt C, Stodel C, Tassan-Got L, Testa E, Volant C. Morjean M, et al. Phys Rev Lett. 2008 Aug 15;101(7):072701. doi: 10.1103/PhysRevLett.101.072701. Epub 2008 Aug 11. Phys Rev Lett. 2008. PMID: 18764526 Free article.
K-shell radiative electron capture with bare 60-MeV/u Kr ions channeled in a Si crystal: Experiments and simulations.
Andriamonje S, Chevallier M, Cohen C, Cue N, Dauvergne D, Dural J, Fujimoto F, Kirsch R, L'Hoir A, Poizat J, Quéré Y, Remillieux J, Röhl C, Rothard H, Rozet JP, Schmaus D, Toulemonde M, Vernhet D. Andriamonje S, et al. Phys Rev A. 1996 Aug;54(2):1404-1416. doi: 10.1103/physreva.54.1404. Phys Rev A. 1996. PMID: 9913606 No abstract available.
Neurotoxicologic concerns with vigabatrin.
Lhoir A. Lhoir A. Acta Clin Belg. 1992;47(5):351-2. doi: 10.1080/17843286.1992.11718253. Acta Clin Belg. 1992. PMID: 1334323 No abstract available.
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