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3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies.
Benitez D, Cabrera M, Hernández P, Boiani L, Lavaggi ML, Di Maio R, Yaluff G, Serna E, Torres S, Ferreira ME, Vera de Bilbao N, Torres E, Pérez-Silanes S, Solano B, Moreno E, Aldana I, López de Ceráin A, Cerecetto H, González M, Monge A. Benitez D, et al. Among authors: boiani l. J Med Chem. 2011 May 26;54(10):3624-36. doi: 10.1021/jm2002469. Epub 2011 May 4. J Med Chem. 2011. PMID: 21506600
Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds.
Aguirre G, Boiani L, Cerecetto H, Di Maio R, González M, Porcal W, Denicola A, Möller M, Thomson L, Tórtora V. Aguirre G, et al. Among authors: boiani l. Bioorg Med Chem. 2005 Dec 1;13(23):6324-35. doi: 10.1016/j.bmc.2005.05.020. Epub 2005 Aug 22. Bioorg Med Chem. 2005. PMID: 16115774
New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies.
Aguirre G, Boiani L, Boiani M, Cerecetto H, Di Maio R, González M, Porcal W, Denicola A, Piro OE, Castellano EE, Sant'Anna CM, Barreiro EJ. Aguirre G, et al. Among authors: boiani l, boiani m. Bioorg Med Chem. 2005 Dec 1;13(23):6336-46. doi: 10.1016/j.bmc.2005.07.072. Epub 2005 Oct 3. Bioorg Med Chem. 2005. PMID: 16202608
Indazole N-oxide derivatives as antiprotozoal agents: synthesis, biological evaluation and mechanism of action studies.
Gerpe A, Aguirre G, Boiani L, Cerecetto H, González M, Olea-Azar C, Rigol C, Maya JD, Morello A, Piro OE, Arán VJ, Azqueta A, de Ceráin AL, Monge A, Rojas MA, Yaluff G. Gerpe A, et al. Among authors: boiani l. Bioorg Med Chem. 2006 May 15;14(10):3467-80. doi: 10.1016/j.bmc.2006.01.007. Epub 2006 Feb 17. Bioorg Med Chem. 2006. PMID: 16483783
Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and structure-activity relationships.
Porcal W, Hernández P, Aguirre G, Boiani L, Boiani M, Merlino A, Ferreira A, Maio RD, Castro A, González M, Cerecetto H. Porcal W, et al. Among authors: boiani l, boiani m. Bioorg Med Chem. 2007 Apr 1;15(7):2768-81. doi: 10.1016/j.bmc.2007.01.009. Epub 2007 Jan 12. Bioorg Med Chem. 2007. PMID: 17287123
In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.
Porcal W, Hernández P, Boiani M, Aguirre G, Boiani L, Chidichimo A, Cazzulo JJ, Campillo NE, Paez JA, Castro A, Krauth-Siegel RL, Davies C, Basombrío MA, González M, Cerecetto H. Porcal W, et al. Among authors: boiani l, boiani m. J Med Chem. 2007 Nov 29;50(24):6004-15. doi: 10.1021/jm070604e. Epub 2007 Oct 26. J Med Chem. 2007. PMID: 17960923
28 results