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Indications for a genetic association of a VCP polymorphism with the pathogenesis of sporadic Paget's disease of bone, but not for TNFSF11 (RANKL) and IL-6 polymorphisms.
Chung PY, Beyens G, de Freitas F, Boonen S, Geusens P, Vanhoenacker F, Verbruggen L, Van Offel J, Goemaere S, Zmierczak HG, Westhovens R, Devogelaer JP, Van Hul W. Chung PY, et al. Among authors: geusens p. Mol Genet Metab. 2011 Jul;103(3):287-92. doi: 10.1016/j.ymgme.2011.03.021. Epub 2011 Mar 31. Mol Genet Metab. 2011. PMID: 21501964
Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone.
Chung PY, Beyens G, Riches PL, Van Wesenbeeck L, de Freitas F, Jennes K, Daroszewska A, Fransen E, Boonen S, Geusens P, Vanhoenacker F, Verbruggen L, Van Offel J, Goemaere S, Zmierczak HG, Westhovens R, Karperien M, Papapoulos S, Ralston SH, Devogelaer JP, Van Hul W. Chung PY, et al. Among authors: geusens p. J Bone Miner Res. 2010 Dec;25(12):2592-605. doi: 10.1002/jbmr.162. Epub 2010 Jun 18. J Bone Miner Res. 2010. PMID: 20564239 Free article.
The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes.
Chung PY, Beyens G, Boonen S, Papapoulos S, Geusens P, Karperien M, Vanhoenacker F, Verbruggen L, Fransen E, Van Offel J, Goemaere S, Zmierczak HG, Westhovens R, Devogelaer JP, Van Hul W. Chung PY, et al. Among authors: geusens p. Hum Genet. 2010 Dec;128(6):615-26. doi: 10.1007/s00439-010-0888-2. Epub 2010 Sep 14. Hum Genet. 2010. PMID: 20839008
Founder effect in different European countries for the recurrent P392L SQSTM1 mutation in Paget's Disease of Bone.
Chung PY, Beyens G, Guañabens N, Boonen S, Papapoulos S, Karperien M, Eekhoff M, Van Wesenbeeck L, Jennes K, Geusens P, Offeciers E, Van Offel J, Westhovens R, Zmierczak H, Devogelaer JP, Van Hul W. Chung PY, et al. Among authors: geusens p. Calcif Tissue Int. 2008 Jul;83(1):34-42. doi: 10.1007/s00223-008-9137-2. Epub 2008 Jun 10. Calcif Tissue Int. 2008. PMID: 18543015
Falls and fractures in postmenopausal women: a review.
Geusens P, Milisen K, Dejaeger E, Boonen S. Geusens P, et al. J Br Menopause Soc. 2003 Sep;9(3):101-6. doi: 10.1258/136218003100322314. J Br Menopause Soc. 2003. PMID: 14670194 Review.
Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study.
Boonen S, Rosen C, Bouillon R, Sommer A, McKay M, Rosen D, Adams S, Broos P, Lenaerts J, Raus J, Vanderschueren D, Geusens P. Boonen S, et al. Among authors: geusens p. J Clin Endocrinol Metab. 2002 Apr;87(4):1593-9. doi: 10.1210/jcem.87.4.8426. J Clin Endocrinol Metab. 2002. PMID: 11932288 Clinical Trial.
Belgian rheumatologists' perception on eligibility of RA patients for anti-TNF treatment matches more closely Dutch rather than Belgian reimbursement criteria.
Geens E, Geusens P, Vanhoof J, Berghs H, Praet J, Esselens G, Lens S, Dufour JP, Vandenberghe M, Van Mullem X, Westhovens R, Verschueren P. Geens E, et al. Among authors: geusens p. Rheumatology (Oxford). 2009 May;48(5):546-50. doi: 10.1093/rheumatology/kep018. Epub 2009 Mar 1. Rheumatology (Oxford). 2009. PMID: 19254920
429 results