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p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin.
Loonat AA, Martin ED, Sarafraz-Shekary N, Tilgner K, Hertz NT, Levin R, Shokat KM, Burlingame AL, Arabacilar P, Uddin S, Thomas M, Marber MS, Clark JE. Loonat AA, et al. Among authors: marber ms. FASEB J. 2019 Dec;33(12):13131-13144. doi: 10.1096/fj.201701545R. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638431 Free PMC article.
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.
De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS. De Nicola GF, et al. Among authors: marber ms. JCI Insight. 2018 Aug 23;3(16):e121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135318 Free PMC article.
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF, Eaton P. Scotcher J, et al. Among authors: marber ms. Nat Commun. 2016 Oct 26;7:13187. doi: 10.1038/ncomms13187. Nat Commun. 2016. PMID: 27782102 Free PMC article.
247 results