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Page 1
Strategies for bringing drug delivery tools into discovery.
Kwong E, Higgins J, Templeton AC. Kwong E, et al. Among authors: higgins j. Int J Pharm. 2011 Jun 30;412(1-2):1-7. doi: 10.1016/j.ijpharm.2011.03.024. Epub 2011 Mar 21. Int J Pharm. 2011. PMID: 21421040 Review.
Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.
Walji AM, Sanchez RI, Clas SD, Nofsinger R, de Lera Ruiz M, Li J, Bennet A, John C, Bennett DJ, Sanders JM, Di Marco CN, Kim SH, Balsells J, Ceglia SS, Dang Q, Manser K, Nissley B, Wai JS, Hafey M, Wang J, Chessen G, Templeton A, Higgins J, Smith R, Wu Y, Grobler J, Coleman PJ. Walji AM, et al. Among authors: higgins j. ChemMedChem. 2015 Feb;10(2):245-52. doi: 10.1002/cmdc.201402393. Epub 2014 Dec 2. ChemMedChem. 2015. PMID: 25469982
Design of prodrugs to enhance colonic absorption by increasing lipophilicity and blocking ionization.
Nofsinger R, Clas SD, Sanchez RI, Walji A, Manser K, Nissley B, Balsells J, Nair A, Dang Q, Bennett DJ, Hafey M, Wang J, Higgins J, Templeton A, Coleman P, Grobler J, Smith R, Wu Y. Nofsinger R, et al. Among authors: higgins j. Pharmaceuticals (Basel). 2014 Feb 24;7(2):207-19. doi: 10.3390/ph7020207. Pharmaceuticals (Basel). 2014. PMID: 24566521 Free PMC article.
Interventions to prevent obesity in children aged 12 to 18 years old.
Spiga F, Tomlinson E, Davies AL, Moore TH, Dawson S, Breheny K, Savović J, Hodder RK, Wolfenden L, Higgins JP, Summerbell CD. Spiga F, et al. Among authors: higgins jp. Cochrane Database Syst Rev. 2024 May 20;5(5):CD015330. doi: 10.1002/14651858.CD015330.pub2. Cochrane Database Syst Rev. 2024. PMID: 38763518 Free PMC article. Review.
Interventions to prevent obesity in children aged 5 to 11 years old.
Spiga F, Davies AL, Tomlinson E, Moore TH, Dawson S, Breheny K, Savović J, Gao Y, Phillips SM, Hillier-Brown F, Hodder RK, Wolfenden L, Higgins JP, Summerbell CD. Spiga F, et al. Among authors: higgins jp. Cochrane Database Syst Rev. 2024 May 20;5(5):CD015328. doi: 10.1002/14651858.CD015328.pub2. Cochrane Database Syst Rev. 2024. PMID: 38763517 Free PMC article. Review.
Recombinant ADAMTS13 for Immune Thrombotic Thrombocytopenic Purpura.
Bendapudi PK, Foy BH, Mueller SB, Liu J, Feingold LM, Burke KE, Cruz W, Chen MY, Lau ES, Goldberg RL, Tatake I, Wilkinson SC, Carney BJ, Stone JR, Park D, Avelino AR, Hassan S, Andrzejewski C, Ruby KN, Friedman KD, Brunker PAR, Leaf RK, Higgins J, Dzik WH, Stefely JA, Makar RS. Bendapudi PK, et al. Among authors: higgins j. N Engl J Med. 2024 May 9;390(18):1690-1698. doi: 10.1056/NEJMoa2402567. N Engl J Med. 2024. PMID: 38718359
2,452 results