Mesecar AD - Search Results

1

Modification of keap1 cysteine residues by sulforaphane.

Hu C, Eggler AL, Mesecar AD, van Breemen RB. Hu C, et al. Among authors: mesecar ad. Chem Res Toxicol. 2011 Apr 18;24(4):515-21. doi: 10.1021/tx100389r. Epub 2011 Mar 10. Chem Res Toxicol. 2011. PMID: 21391649 Free PMC article.

2

Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.

Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL. Yao J, et al. Among authors: mesecar ad. Chem Res Toxicol. 2003 May;16(5):668-75. doi: 10.1021/tx0340549. Chem Res Toxicol. 2003. PMID: 12755597

3

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.

Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Eggler AL, et al. Among authors: mesecar ad. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10070-5. doi: 10.1073/pnas.0502402102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006525 Free PMC article.

4

Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.

Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL. Dietz BM, et al. Among authors: mesecar ad. Chem Res Toxicol. 2005 Aug;18(8):1296-305. doi: 10.1021/tx050058x. Chem Res Toxicol. 2005. PMID: 16097803 Free PMC article.

5

Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.

Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Liu G, et al. Among authors: mesecar ad. Anal Chem. 2005 Oct 1;77(19):6407-14. doi: 10.1021/ac050892r. Anal Chem. 2005. PMID: 16194107

6

Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent.

Eggler AL, Luo Y, van Breemen RB, Mesecar AD. Eggler AL, et al. Among authors: mesecar ad. Chem Res Toxicol. 2007 Dec;20(12):1878-84. doi: 10.1021/tx700217c. Epub 2007 Oct 13. Chem Res Toxicol. 2007. PMID: 17935299

7

Sites of alkylation of human Keap1 by natural chemoprevention agents.

Luo Y, Eggler AL, Liu D, Liu G, Mesecar AD, van Breemen RB. Luo Y, et al. Among authors: mesecar ad. J Am Soc Mass Spectrom. 2007 Dec;18(12):2226-32. doi: 10.1016/j.jasms.2007.09.015. Epub 2007 Oct 2. J Am Soc Mass Spectrom. 2007. PMID: 17980616 Free PMC article.

8

Prospective type 1 and type 2 disulfides of Keap1 protein.

Holland R, Hawkins AE, Eggler AL, Mesecar AD, Fabris D, Fishbein JC. Holland R, et al. Among authors: mesecar ad. Chem Res Toxicol. 2008 Oct;21(10):2051-60. doi: 10.1021/tx800226m. Epub 2008 Aug 26. Chem Res Toxicol. 2008. PMID: 18729328 Free PMC article.

9

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.

Eggler AL, Small E, Hannink M, Mesecar AD. Eggler AL, et al. Among authors: mesecar ad. Biochem J. 2009 Jul 29;422(1):171-80. doi: 10.1042/BJ20090471. Biochem J. 2009. PMID: 19489739 Free PMC article.

10

Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3-RINGBox1 protein complex and elucidation of its quaternary structure with Keap1.

Small E, Eggler A, Mesecar AD. Small E, et al. Among authors: mesecar ad. Biochem Biophys Res Commun. 2010 Oct 1;400(4):471-5. doi: 10.1016/j.bbrc.2010.08.062. Epub 2010 Aug 22. Biochem Biophys Res Commun. 2010. PMID: 20735986 Free PMC article.

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