Saecker RM - Search Results

1

Mechanism of bacterial transcription initiation: RNA polymerase - promoter binding, isomerization to initiation-competent open complexes, and initiation of RNA synthesis.

Saecker RM, Record MT Jr, Dehaseth PL. Saecker RM, et al. J Mol Biol. 2011 Oct 7;412(5):754-71. doi: 10.1016/j.jmb.2011.01.018. Epub 2011 Mar 1. J Mol Biol. 2011. PMID: 21371479 Free PMC article.

2

Compensating effects of opposing changes in putrescine (2+) and K+ concentrations on lac repressor-lac operator binding: in vitro thermodynamic analysis and in vivo relevance.

Capp MW, Cayley DS, Zhang W, Guttman HJ, Melcher SE, Saecker RM, Anderson CF, Record MT Jr. Capp MW, et al. Among authors: saecker rm. J Mol Biol. 1996 Apr 26;258(1):25-36. doi: 10.1006/jmbi.1996.0231. J Mol Biol. 1996. PMID: 8613989

3

Cooperative and anticooperative effects in binding of the first and second plasmid Osym operators to a LacI tetramer: evidence for contributions of non-operator DNA binding by wrapping and looping.

Levandoski MM, Tsodikov OV, Frank DE, Melcher SE, Saecker RM, Record MT Jr. Levandoski MM, et al. Among authors: saecker rm. J Mol Biol. 1996 Aug 2;260(5):697-717. doi: 10.1006/jmbi.1996.0431. J Mol Biol. 1996. PMID: 8709149

4

Thermodynamics of the interactions of lac repressor with variants of the symmetric lac operator: effects of converting a consensus site to a non-specific site.

Frank DE, Saecker RM, Bond JP, Capp MW, Tsodikov OV, Melcher SE, Levandoski MM, Record MT Jr. Frank DE, et al. Among authors: saecker rm. J Mol Biol. 1997 Apr 18;267(5):1186-206. doi: 10.1006/jmbi.1997.0920. J Mol Biol. 1997. PMID: 9150406

5

DNA footprints of the two kinetically significant intermediates in formation of an RNA polymerase-promoter open complex: evidence that interactions with start site and downstream DNA induce sequential conformational changes in polymerase and DNA.

Craig ML, Tsodikov OV, McQuade KL, Schlax PE Jr, Capp MW, Saecker RM, Record MT Jr. Craig ML, et al. Among authors: saecker rm. J Mol Biol. 1998 Nov 6;283(4):741-56. doi: 10.1006/jmbi.1998.2129. J Mol Biol. 1998. PMID: 9790837

6

Quantitative analysis of multiple-hit footprinting studies to characterize DNA conformational changes in protein-DNA complexes: application to DNA opening by Esigma70 RNA polymerase.

Tsodikov OV, Craig ML, Saecker RM, Record MT Jr. Tsodikov OV, et al. Among authors: saecker rm. J Mol Biol. 1998 Nov 6;283(4):757-69. doi: 10.1006/jmbi.1998.2130. J Mol Biol. 1998. PMID: 9790838

7

Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: interpretation in terms of coupled processes of formation and association of single-stranded helices.

Holbrook JA, Capp MW, Saecker RM, Record MT Jr. Holbrook JA, et al. Among authors: saecker rm. Biochemistry. 1999 Jun 29;38(26):8409-22. doi: 10.1021/bi990043w. Biochemistry. 1999. PMID: 10387087

8

Wrapping of flanking non-operator DNA in lac repressor-operator complexes: implications for DNA looping.

Tsodikov OV, Saecker RM, Melcher SE, Levandoski MM, Frank DE, Capp MW, Record MT Jr. Tsodikov OV, et al. Among authors: saecker rm. J Mol Biol. 1999 Dec 3;294(3):639-55. doi: 10.1006/jmbi.1999.3283. J Mol Biol. 1999. PMID: 10610786

9

Thermodynamic analysis of interactions between denaturants and protein surface exposed on unfolding: interpretation of urea and guanidinium chloride m-values and their correlation with changes in accessible surface area (ASA) using preferential interaction coefficients and the local-bulk domain model.

Courtenay ES, Capp MW, Saecker RM, Record MT Jr. Courtenay ES, et al. Among authors: saecker rm. Proteins. 2000;Suppl 4:72-85. doi: 10.1002/1097-0134(2000)41:4+<72::aid-prot70>3.0.co;2-7. Proteins. 2000. PMID: 11013402

10

Specific and non-specific interactions of integration host factor with DNA: thermodynamic evidence for disruption of multiple IHF surface salt-bridges coupled to DNA binding.

Holbrook JA, Tsodikov OV, Saecker RM, Record MT Jr. Holbrook JA, et al. Among authors: saecker rm. J Mol Biol. 2001 Jul 6;310(2):379-401. doi: 10.1006/jmbi.2001.4768. J Mol Biol. 2001. PMID: 11428896

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