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TcdB or not TcdB: a tale of two Clostridium difficile toxins.
Carter GP, Awad MM, Kelly ML, Rood JI, Lyras D. Carter GP, et al. Among authors: rood ji. Future Microbiol. 2011 Feb;6(2):121-3. doi: 10.2217/fmb.10.169. Future Microbiol. 2011. PMID: 21366410 Free article. No abstract available.
The alpha-toxin of Clostridium septicum is essential for virulence.
Kennedy CL, Krejany EO, Young LF, O'Connor JR, Awad MM, Boyd RL, Emmins JJ, Lyras D, Rood JI. Kennedy CL, et al. Among authors: rood ji. Mol Microbiol. 2005 Sep;57(5):1357-66. doi: 10.1111/j.1365-2958.2005.04774.x. Mol Microbiol. 2005. PMID: 16102005 Free article.
Toxin B is essential for virulence of Clostridium difficile.
Lyras D, O'Connor JR, Howarth PM, Sambol SP, Carter GP, Phumoonna T, Poon R, Adams V, Vedantam G, Johnson S, Gerding DN, Rood JI. Lyras D, et al. Among authors: rood ji. Nature. 2009 Apr 30;458(7242):1176-9. doi: 10.1038/nature07822. Epub 2009 Mar 1. Nature. 2009. PMID: 19252482 Free PMC article.
Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections.
Carter GP, Chakravorty A, Pham Nguyen TA, Mileto S, Schreiber F, Li L, Howarth P, Clare S, Cunningham B, Sambol SP, Cheknis A, Figueroa I, Johnson S, Gerding D, Rood JI, Dougan G, Lawley TD, Lyras D. Carter GP, et al. Among authors: rood ji. mBio. 2015 Jun 2;6(3):e00551. doi: 10.1128/mBio.00551-15. mBio. 2015. PMID: 26037121 Free PMC article.
CdtR Regulates TcdA and TcdB Production in Clostridium difficile.
Lyon SA, Hutton ML, Rood JI, Cheung JK, Lyras D. Lyon SA, et al. Among authors: rood ji. PLoS Pathog. 2016 Jul 14;12(7):e1005758. doi: 10.1371/journal.ppat.1005758. eCollection 2016 Jul. PLoS Pathog. 2016. PMID: 27414650 Free PMC article.
Construction and analysis of chromosomal Clostridium difficile mutants.
O'Connor JR, Lyras D, Farrow KA, Adams V, Powell DR, Hinds J, Cheung JK, Rood JI. O'Connor JR, et al. Among authors: rood ji. Mol Microbiol. 2006 Sep;61(5):1335-51. doi: 10.1111/j.1365-2958.2006.05315.x. Mol Microbiol. 2006. PMID: 16925561 Free article.
242 results