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Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies.
Kauh J, Chanel-Vos C, Escuin D, Fanucchi MP, Harvey RD, Saba N, Shin DM, Gal A, Pan L, Kutner M, Ramalingam SS, Bender L, Marcus A, Giannakakou P, Khuri FR. Kauh J, et al. Among authors: giannakakou p. Cancer. 2011 Sep 1;117(17):4049-59. doi: 10.1002/cncr.26004. Epub 2011 Mar 1. Cancer. 2011. PMID: 21365629 Free PMC article. Clinical Trial.
Farnesyltransferase inhibitors reverse taxane resistance.
Marcus AI, O'Brate AM, Buey RM, Zhou J, Thomas S, Khuri FR, Andreu JM, Díaz F, Giannakakou P. Marcus AI, et al. Among authors: giannakakou p. Cancer Res. 2006 Sep 1;66(17):8838-46. doi: 10.1158/0008-5472.CAN-06-0699. Cancer Res. 2006. PMID: 16951201 Free PMC article.
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
Kang SH, Cho HT, Devi S, Zhang Z, Escuin D, Liang Z, Mao H, Brat DJ, Olson JJ, Simons JW, Lavallee TM, Giannakakou P, Van Meir EG, Shim H. Kang SH, et al. Among authors: giannakakou p. Cancer Res. 2006 Dec 15;66(24):11991-7. doi: 10.1158/0008-5472.CAN-06-1320. Cancer Res. 2006. PMID: 17178898
Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer.
Darshan MS, Loftus MS, Thadani-Mulero M, Levy BP, Escuin D, Zhou XK, Gjyrezi A, Chanel-Vos C, Shen R, Tagawa ST, Bander NH, Nanus DM, Giannakakou P. Darshan MS, et al. Among authors: giannakakou p. Cancer Res. 2011 Sep 15;71(18):6019-29. doi: 10.1158/0008-5472.CAN-11-1417. Epub 2011 Jul 28. Cancer Res. 2011. PMID: 21799031 Free PMC article.
Exploitation of the HIF axis for cancer therapy.
Escuin D, Simons JW, Giannakakou P. Escuin D, et al. Among authors: giannakakou p. Cancer Biol Ther. 2004 Jul;3(7):608-11. doi: 10.4161/cbt.3.7.954. Epub 2004 Jul 29. Cancer Biol Ther. 2004. PMID: 15197342 Review.
111 results