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Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance.
Org Biomol Chem. 2011 Jun 7;9(11):4057-63. doi: 10.1039/c0ob01133a. Epub 2011 Mar 1.
Org Biomol Chem. 2011.
PMID: 21365081
Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance.
Berkov-Zrihen Y, Green KD, Labby KJ, Feldman M, Garneau-Tsodikova S, Fridman M.
Berkov-Zrihen Y, et al.
J Med Chem. 2013 Jul 11;56(13):5613-25. doi: 10.1021/jm400707f. Epub 2013 Jul 1.
J Med Chem. 2013.
PMID: 23786357
Free PMC article.
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Site-selective displacement of tobramycin hydroxyls for preparation of antimicrobial cationic amphiphiles.
Berkov-Zrihen Y, Herzog IM, Feldman M, Fridman M.
Berkov-Zrihen Y, et al.
Org Lett. 2013 Dec 20;15(24):6144-7. doi: 10.1021/ol4030138. Epub 2013 Nov 13.
Org Lett. 2013.
PMID: 24224657
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6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes.
Herzog IM, Green KD, Berkov-Zrihen Y, Feldman M, Vidavski RR, Eldar-Boock A, Satchi-Fainaro R, Eldar A, Garneau-Tsodikova S, Fridman M.
Herzog IM, et al. Among authors: berkov zrihen y.
Angew Chem Int Ed Engl. 2012 Jun 4;51(23):5652-6. doi: 10.1002/anie.201200761. Epub 2012 Apr 12.
Angew Chem Int Ed Engl. 2012.
PMID: 22499286
Free PMC article.
No abstract available.
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Di-alkylated paromomycin derivatives: targeting the membranes of gram positive pathogens that cause skin infections.
Berkov-Zrihen Y, Herzog IM, Feldman M, Sonn-Segev A, Roichman Y, Fridman M.
Berkov-Zrihen Y, et al.
Bioorg Med Chem. 2013 Jun 15;21(12):3624-31. doi: 10.1016/j.bmc.2013.03.046. Epub 2013 Apr 2.
Bioorg Med Chem. 2013.
PMID: 23602621
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Tobramycin and nebramine as pseudo-oligosaccharide scaffolds for the development of antimicrobial cationic amphiphiles.
Berkov-Zrihen Y, Herzog IM, Benhamou RI, Feldman M, Steinbuch KB, Shaul P, Lerer S, Eldar A, Fridman M.
Berkov-Zrihen Y, et al.
Chemistry. 2015 Mar 9;21(11):4340-9. doi: 10.1002/chem.201406404. Epub 2015 Feb 4.
Chemistry. 2015.
PMID: 25652188
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One-Pot Chemoenzymatic Cascade for Labeling of the Epigenetic Marker 5-Hydroxymethylcytosine.
Nifker G, Levy-Sakin M, Berkov-Zrihen Y, Shahal T, Gabrieli T, Fridman M, Ebenstein Y.
Nifker G, et al. Among authors: berkov zrihen y.
Chembiochem. 2015 Sep 7;16(13):1857-1860. doi: 10.1002/cbic.201500329. Epub 2015 Jul 27.
Chembiochem. 2015.
PMID: 26147952
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