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Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas.
Looyenga BD, Furge KA, Dykema KJ, Koeman J, Swiatek PJ, Giordano TJ, West AB, Resau JH, Teh BT, MacKeigan JP. Looyenga BD, et al. Among authors: dykema kj. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1439-44. doi: 10.1073/pnas.1012500108. Epub 2011 Jan 10. Proc Natl Acad Sci U S A. 2011. PMID: 21220347 Free PMC article.
Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.
Andersen NJ, Nickoloff BJ, Dykema KJ, Boguslawski EA, Krivochenitser RI, Froman RE, Dawes MJ, Baker LH, Thomas DG, Kamstock DA, Kitchell BE, Furge KA, Duesbery NS. Andersen NJ, et al. Among authors: dykema kj. Mol Cancer Ther. 2013 Sep;12(9):1701-14. doi: 10.1158/1535-7163.MCT-12-0893. Epub 2013 Jun 26. Mol Cancer Ther. 2013. PMID: 23804705 Free PMC article.
Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.
Monsma DJ, Cherba DM, Eugster EE, Dylewski DL, Davidson PT, Peterson CA, Borgman AS, Winn ME, Dykema KJ, Webb CP, MacKeigan JP, Duesbery NS, Nickoloff BJ, Monks NR. Monsma DJ, et al. Among authors: dykema kj. Am J Cancer Res. 2015 Mar 15;5(4):1507-18. eCollection 2015. Am J Cancer Res. 2015. PMID: 26101714 Free PMC article.
52 results