Potter BV - Search Results

1

Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents.

Zaraei SO, Dohle W, Anbar HS, El-Gamal R, Leblond B, Foster PA, Al-Tel TH, Potter BVL, El-Gamal MI. Zaraei SO, et al. Among authors: potter bvl. Bioorg Med Chem. 2024 Mar 1;101:117645. doi: 10.1016/j.bmc.2024.117645. Epub 2024 Feb 16. Bioorg Med Chem. 2024. PMID: 38401456

2

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.

Márquez-Moñino MÁ, Ortega-García R, Whitfield H, Riley AM, Infantes L, Garrett SW, Shipton ML, Brearley CA, Potter BVL, González B. Márquez-Moñino MÁ, et al. Among authors: potter bvl. Nat Commun. 2024 Feb 19;15(1):1502. doi: 10.1038/s41467-024-45917-5. Nat Commun. 2024. PMID: 38374076 Free PMC article.

3

Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischemia-reperfusion injury by elevating plasma adiponectin.

Fu L, Du J, Furkert D, Shipton ML, Liu X, Aguirre T, Chin AC, Riley AM, Potter BVL, Fiedler D, Zhang X, Zhu Y, Fu C. Fu L, et al. Among authors: potter bvl. Cardiovasc Res. 2024 Jan 22:cvae017. doi: 10.1093/cvr/cvae017. Online ahead of print. Cardiovasc Res. 2024. PMID: 38252884

4

Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1).

Whitfield HL, Rodriguez RF, Shipton ML, Li AWH, Riley AM, Potter BVL, Hemmings AM, Brearley CA. Whitfield HL, et al. Among authors: potter bvl. Biochemistry. 2024 Jan 2;63(1):42-52. doi: 10.1021/acs.biochem.3c00404. Epub 2023 Dec 26. Biochemistry. 2024. PMID: 38146842 Free PMC article.

5

Promising drug candidates for the treatment of polycystic ovary syndrome (PCOS) as alternatives to the classical medication metformin.

Anbar HS, Vahora NY, Shah HL, Azam MM, Islam T, Hersi F, Omar HA, Dohle W, Potter BVL, El-Gamal MI. Anbar HS, et al. Among authors: potter bvl. Eur J Pharmacol. 2023 Dec 5;960:176119. doi: 10.1016/j.ejphar.2023.176119. Epub 2023 Oct 16. Eur J Pharmacol. 2023. PMID: 37852569

6

Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs.

Hostachy S, Wang H, Zong G, Franke K, Riley AM, Schmieder P, Potter BVL, Shears SB, Fiedler D. Hostachy S, et al. Among authors: potter bvl. Chemistry. 2023 Dec 1;29(67):e202302426. doi: 10.1002/chem.202302426. Epub 2023 Oct 19. Chemistry. 2023. PMID: 37773020 Free PMC article.

7

2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells.

Franco YA, de Moraes MO Jr, Carvalho LAC, Dohle W, da Silva RO, Noma IHY, Lima K, Potter BVL, Machado-Neto JA, Maria-Engler SS. Franco YA, et al. Among authors: potter bvl. Int J Mol Sci. 2023 Jul 11;24(14):11314. doi: 10.3390/ijms241411314. Int J Mol Sci. 2023. PMID: 37511073 Free PMC article.

8

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein.

Sacerdoti M, Gross LZF, Riley AM, Zehnder K, Ghode A, Klinke S, Anand GS, Paris K, Winkel A, Herbrand AK, Godage HY, Cozier GE, Süß E, Schulze JO, Pastor-Flores D, Bollini M, Cappellari MV, Svergun D, Gräwert MA, Aramendia PF, Leroux AE, Potter BVL, Camacho CJ, Biondi RM. Sacerdoti M, et al. Among authors: potter bvl. Sci Signal. 2023 Jun 13;16(789):eadd3184. doi: 10.1126/scisignal.add3184. Epub 2023 Jun 13. Sci Signal. 2023. PMID: 37311034 Free PMC article.

9

Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP₅.

Shipton ML, Jamion FA, Wheeler S, Riley AM, Plasser F, Potter BVL, Butler SJ. Shipton ML, et al. Among authors: potter bvl. Chem Sci. 2023 Apr 13;14(19):4979-4985. doi: 10.1039/d2sc06812e. eCollection 2023 May 17. Chem Sci. 2023. PMID: 37206391 Free PMC article.

10

2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca²⁺ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.

Hosang L, Löhndorf A, Dohle W, Rosche A, Marry S, Diercks BP, Müller-Kirschbaum LC, Flügel LT, Potter BVL, Odoardi F, Guse AH, Flügel A. Hosang L, et al. Among authors: potter bvl. Biochim Biophys Acta Mol Cell Res. 2023 Aug;1870(6):119485. doi: 10.1016/j.bbamcr.2023.119485. Epub 2023 May 6. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 37150482 Free PMC article.

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