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A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility.
Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD; International Multiple Sclerosis Genetics Consortium. Bush WS, et al. Among authors: haines jl. Genes Immun. 2011 Jul;12(5):335-40. doi: 10.1038/gene.2011.3. Epub 2011 Feb 24. Genes Immun. 2011. PMID: 21346779 Free PMC article.
A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis.
Ban M, McCauley JL, Zuvich R, Baker A, Bergamaschi L, Cox M, Kemppinen A, D'Alfonso S, Guerini FR, Lechner-Scott J, Dudbridge F, Wason J, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, Sexton D, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines J, Compston A, Sawcer S. Ban M, et al. Among authors: haines j. Genes Immun. 2010 Dec;11(8):660-4. doi: 10.1038/gene.2010.36. Epub 2010 Jun 24. Genes Immun. 2010. PMID: 20574445 Free PMC article.
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility.
Damotte V, Guillot-Noel L, Patsopoulos NA, Madireddy L, El Behi M; International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2; De Jager PL, Baranzini SE, Cournu-Rebeix I, Fontaine B. Damotte V, et al. Genes Immun. 2014 Mar;15(2):126-32. doi: 10.1038/gene.2013.70. Epub 2014 Jan 16. Genes Immun. 2014. PMID: 24430173 Free article.
Overview of linkage analysis in complex traits.
Bush WS, Haines J. Bush WS, et al. Curr Protoc Hum Genet. 2010 Jan;Chapter 1:Unit 1.9.1-18. doi: 10.1002/0471142905.hg0109s64. Curr Protoc Hum Genet. 2010. PMID: 20063263
Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans.
Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Brassat D, et al. Among authors: haines jl. Genes Immun. 2006 Jun;7(4):310-5. doi: 10.1038/sj.gene.6364299. Epub 2006 Apr 20. Genes Immun. 2006. PMID: 16625214 Free PMC article.
Genetics and pathogenesis of multiple sclerosis.
Zuvich RL, McCauley JL, Pericak-Vance MA, Haines JL. Zuvich RL, et al. Among authors: haines jl. Semin Immunol. 2009 Dec;21(6):328-33. doi: 10.1016/j.smim.2009.08.003. Epub 2009 Sep 22. Semin Immunol. 2009. PMID: 19775910 Free PMC article. Review.
704 results