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Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status.
J Dermatol Sci. 2011 Apr;62(1):22-35. doi: 10.1016/j.jdermsci.2011.01.006. Epub 2011 Jan 25.
J Dermatol Sci. 2011.
PMID: 21324654
Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine.
Hammerová J, Uldrijan S, Táborská E, Vaculová AH, Slaninová I.
Hammerová J, et al.
Biol Chem. 2012 Jul;393(7):647-58. doi: 10.1515/hsz-2011-0279.
Biol Chem. 2012.
PMID: 22944669
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Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells.
Slunská Z, Gelnarová E, Hammerová J, Táborská E, Slaninová I.
Slunská Z, et al. Among authors: hammerova j.
Toxicol In Vitro. 2010 Apr;24(3):697-706. doi: 10.1016/j.tiv.2010.01.012. Epub 2010 Feb 4.
Toxicol In Vitro. 2010.
PMID: 20138138
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