Rosado LA - Search Results

1

Recombinant Escherichia coli GMP reductase: kinetic, catalytic and chemical mechanisms, and thermodynamics of enzyme-ligand binary complex formation.

Martinelli LK, Ducati RG, Rosado LA, Breda A, Selbach BP, Santos DS, Basso LA. Martinelli LK, et al. Among authors: rosado la. Mol Biosyst. 2011 Apr;7(4):1289-305. doi: 10.1039/c0mb00245c. Epub 2011 Feb 7. Mol Biosyst. 2011. PMID: 21298178

2

Kinetic mechanism determination and analysis of metal requirement of dehydroquinate synthase from Mycobacterium tuberculosis H37Rv: an essential step in the function-based rational design of anti-TB drugs.

de Mendonça JD, Adachi O, Rosado LA, Ducati RG, Santos DS, Basso LA. de Mendonça JD, et al. Among authors: rosado la. Mol Biosyst. 2011 Jan;7(1):119-28. doi: 10.1039/c0mb00085j. Epub 2010 Oct 26. Mol Biosyst. 2011. PMID: 20978656

3

Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase.

Breda A, Rosado LA, Lorenzini DM, Basso LA, Santos DS. Breda A, et al. Among authors: rosado la. Mol Biosyst. 2012 Feb;8(2):572-86. doi: 10.1039/c1mb05402c. Epub 2011 Nov 11. Mol Biosyst. 2012. PMID: 22075667

4

The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.

Rosado LA, Vasconcelos IB, Palma MS, Frappier V, Najmanovich RJ, Santos DS, Basso LA. Rosado LA, et al. PLoS One. 2013 May 6;8(5):e61918. doi: 10.1371/journal.pone.0061918. Print 2013. PLoS One. 2013. PMID: 23671579 Free PMC article.

5

Biochemical characterization of recombinant nucleoside hydrolase from Mycobacterium tuberculosis H37Rv.

Wink PL, Sanchez Quitian ZA, Rosado LA, Rodrigues Vda S Jr, Petersen GO, Lorenzini DM, Lipinski-Paes T, Saraiva Macedo Timmers LF, de Souza ON, Basso LA, Santos DS. Wink PL, et al. Among authors: rosado la. Arch Biochem Biophys. 2013 Oct 15;538(2):80-94. doi: 10.1016/j.abb.2013.08.011. Epub 2013 Aug 26. Arch Biochem Biophys. 2013. PMID: 23988349 Free article.

6

Mycobacterium tuberculosis beta-ketoacyl-ACP reductase: alpha-secondary kinetic isotope effects and kinetic and equilibrium mechanisms of substrate binding.

Silva RG, Rosado LA, Santos DS, Basso LA. Silva RG, et al. Among authors: rosado la. Arch Biochem Biophys. 2008 Mar 1;471(1):1-10. doi: 10.1016/j.abb.2007.12.002. Epub 2007 Dec 10. Arch Biochem Biophys. 2008. PMID: 18155153

7

UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation.

Rostirolla DC, Breda A, Rosado LA, Palma MS, Basso LA, Santos DS. Rostirolla DC, et al. Among authors: rosado la. Arch Biochem Biophys. 2011 Jan 15;505(2):202-12. doi: 10.1016/j.abb.2010.10.019. Epub 2010 Oct 28. Arch Biochem Biophys. 2011. PMID: 21035424 Free article.

8

Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23).

Nunes JE, Ducati RG, Breda A, Rosado LA, de Souza BM, Palma MS, Santos DS, Basso LA. Nunes JE, et al. Among authors: rosado la. Arch Biochem Biophys. 2011 Aug 15;512(2):143-53. doi: 10.1016/j.abb.2011.05.020. Epub 2011 Jun 6. Arch Biochem Biophys. 2011. PMID: 21672513 Free article.

9

Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase.

Breda A, Machado P, Rosado LA, Souto AA, Santos DS, Basso LA. Breda A, et al. Among authors: rosado la. Eur J Med Chem. 2012 Aug;54:113-22. doi: 10.1016/j.ejmech.2012.04.031. Epub 2012 Apr 30. Eur J Med Chem. 2012. PMID: 22608674

10

Biochemical characterization of uracil phosphoribosyltransferase from Mycobacterium tuberculosis.

Villela AD, Ducati RG, Rosado LA, Bloch CJ, Prates MV, Gonçalves DC, Ramos CH, Basso LA, Santos DS. Villela AD, et al. Among authors: rosado la. PLoS One. 2013;8(2):e56445. doi: 10.1371/journal.pone.0056445. Epub 2013 Feb 12. PLoS One. 2013. PMID: 23424660 Free PMC article.

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