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Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes.
Palazón A, Teijeira A, Martínez-Forero I, Hervás-Stubbs S, Roncal C, Peñuelas I, Dubrot J, Morales-Kastresana A, Pérez-Gracia JL, Ochoa MC, Ochoa-Callejero L, Martínez A, Luque A, Dinchuk J, Rouzaut A, Jure-Kunkel M, Melero I. Palazón A, et al. Among authors: melero i. Cancer Res. 2011 Feb 1;71(3):801-11. doi: 10.1158/0008-5472.CAN-10-1733. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266358
Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.
Feijoó E, Alfaro C, Mazzolini G, Serra P, Peñuelas I, Arina A, Huarte E, Tirapu I, Palencia B, Murillo O, Ruiz J, Sangro B, Richter JA, Prieto J, Melero I. Feijoó E, et al. Among authors: melero i. Int J Cancer. 2005 Aug 20;116(2):275-81. doi: 10.1002/ijc.21046. Int J Cancer. 2005. PMID: 15800914 Free article. Clinical Trial.
Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.
Tirapu I, Huarte E, Guiducci C, Arina A, Zaratiegui M, Murillo O, Gonzalez A, Berasain C, Berraondo P, Fortes P, Prieto J, Colombo MP, Chen L, Melero I. Tirapu I, et al. Among authors: melero i. Cancer Res. 2006 Feb 15;66(4):2442-50. doi: 10.1158/0008-5472.CAN-05-1681. Cancer Res. 2006. PMID: 16489051 Free article.
Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.
Huarte E, Larrea E, Hernández-Alcoceba R, Alfaro C, Murillo O, Arina A, Tirapu I, Azpilicueta A, Hervás-Stubbs S, Bortolanza S, Pérez-Gracia JL, Civeira MP, Prieto J, Riezu-Boj JI, Melero I. Huarte E, et al. Among authors: melero i. Mol Ther. 2006 Jul;14(1):129-38. doi: 10.1016/j.ymthe.2006.02.015. Epub 2006 Apr 19. Mol Ther. 2006. PMID: 16627004 Free article.
359 results