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Detection of nonsterol isoprenoids by HPLC-MS/MS.
Henneman L, van Cruchten AG, Denis SW, Amolins MW, Placzek AT, Gibbs RA, Kulik W, Waterham HR. Henneman L, et al. Anal Biochem. 2008 Dec 1;383(1):18-24. doi: 10.1016/j.ab.2008.08.023. Epub 2008 Aug 30. Anal Biochem. 2008. PMID: 18782552 Free PMC article.
Molecular and cellular consequences of mevalonate kinase deficiency.
Politiek FA, Turkenburg M, Henneman L, Ofman R, Waterham HR. Politiek FA, et al. Among authors: henneman l. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167177. doi: 10.1016/j.bbadis.2024.167177. Epub 2024 Apr 16. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38636615 Free article.
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
Zingg D, Bhin J, Yemelyanenko J, Kas SM, Rolfs F, Lutz C, Lee JK, Klarenbeek S, Silverman IM, Annunziato S, Chan CS, Piersma SR, Eijkman T, Badoux M, Gogola E, Siteur B, Sprengers J, de Klein B, de Goeij-de Haas RR, Riedlinger GM, Ke H, Madison R, Drenth AP, van der Burg E, Schut E, Henneman L, van Miltenburg MH, Proost N, Zhen H, Wientjens E, de Bruijn R, de Ruiter JR, Boon U, de Korte-Grimmerink R, van Gerwen B, Féliz L, Abou-Alfa GK, Ross JS, van de Ven M, Rottenberg S, Cuppen E, Chessex AV, Ali SM, Burn TC, Jimenez CR, Ganesan S, Wessels LFA, Jonkers J. Zingg D, et al. Among authors: henneman l. Nature. 2022 Aug;608(7923):609-617. doi: 10.1038/s41586-022-05066-5. Epub 2022 Aug 10. Nature. 2022. PMID: 35948633 Free PMC article. Clinical Trial.
Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.
Henneman L, van Miltenburg MH, Michalak EM, Braumuller TM, Jaspers JE, Drenth AP, de Korte-Grimmerink R, Gogola E, Szuhai K, Schlicker A, Bin Ali R, Pritchard C, Huijbers IJ, Berns A, Rottenberg S, Jonkers J. Henneman L, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8409-14. doi: 10.1073/pnas.1500223112. Epub 2015 Jun 22. Proc Natl Acad Sci U S A. 2015. PMID: 26100884 Free PMC article.
TRPM7 is required for breast tumor cell metastasis.
Middelbeek J, Kuipers AJ, Henneman L, Visser D, Eidhof I, van Horssen R, Wieringa B, Canisius SV, Zwart W, Wessels LF, Sweep FC, Bult P, Span PN, van Leeuwen FN, Jalink K. Middelbeek J, et al. Among authors: henneman l. Cancer Res. 2012 Aug 15;72(16):4250-61. doi: 10.1158/0008-5472.CAN-11-3863. Epub 2012 Aug 7. Cancer Res. 2012. PMID: 22871386 Free article.
Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.
Annunziato S, de Ruiter JR, Henneman L, Brambillasca CS, Lutz C, Vaillant F, Ferrante F, Drenth AP, van der Burg E, Siteur B, van Gerwen B, de Bruijn R, van Miltenburg MH, Huijbers IJ, van de Ven M, Visvader JE, Lindeman GJ, Wessels LFA, Jonkers J. Annunziato S, et al. Among authors: henneman l. Nat Commun. 2019 Jan 23;10(1):397. doi: 10.1038/s41467-019-08301-2. Nat Commun. 2019. PMID: 30674894 Free PMC article.
225 results