Breyer RM - Search Results

1

Evidence for the presence of a critical disulfide bond in the mouse EP3γ receptor.

Downey JD, Sanders CR, Breyer RM. Downey JD, et al. Among authors: breyer rm. Prostaglandins Other Lipid Mediat. 2011 Feb;94(1-2):53-8. doi: 10.1016/j.prostaglandins.2010.12.007. Epub 2011 Jan 12. Prostaglandins Other Lipid Mediat. 2011. PMID: 21236356 Free PMC article.

2

Development of an in vivo active, dual EP1 and EP3 selective antagonist based on a novel acyl sulfonamide bioisostere.

Downey JD, Saleh SA, Bridges TM, Morrison RD, Daniels JS, Lindsley CW, Breyer RM. Downey JD, et al. Among authors: breyer rm. Bioorg Med Chem Lett. 2013 Jan 1;23(1):37-41. doi: 10.1016/j.bmcl.2012.11.046. Epub 2012 Nov 24. Bioorg Med Chem Lett. 2013. PMID: 23218714 Free PMC article.

3

The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.

Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM. Ceddia RP, et al. Among authors: breyer rm. Prostaglandins Other Lipid Mediat. 2019 Oct;144:106353. doi: 10.1016/j.prostaglandins.2019.106353. Epub 2019 Jul 2. Prostaglandins Other Lipid Mediat. 2019. PMID: 31276827 Free PMC article.

4

Solution NMR spectroscopy of the human vasopressin V2 receptor, a G protein-coupled receptor.

Tian C, Breyer RM, Kim HJ, Karra MD, Friedman DB, Karpay A, Sanders CR. Tian C, et al. Among authors: breyer rm. J Am Chem Soc. 2005 Jun 8;127(22):8010-1. doi: 10.1021/ja051161b. J Am Chem Soc. 2005. PMID: 15926814

5

CHOBIMALT: a cholesterol-based detergent.

Howell SC, Mittal R, Huang L, Travis B, Breyer RM, Sanders CR. Howell SC, et al. Among authors: breyer rm. Biochemistry. 2010 Nov 9;49(44):9572-83. doi: 10.1021/bi101334j. Biochemistry. 2010. PMID: 20919740 Free PMC article.

6

PGE2 decreases reactivity of human platelets by activating EP2 and EP4.

Smith JP, Haddad EV, Downey JD, Breyer RM, Boutaud O. Smith JP, et al. Among authors: breyer rm. Thromb Res. 2010 Jul;126(1):e23-9. doi: 10.1016/j.thromres.2010.04.003. Epub 2010 May 8. Thromb Res. 2010. PMID: 20451959 Free PMC article.

7

Extracellular loop II modulates GTP sensitivity of the prostaglandin EP3 receptor.

Natarajan C, Hata AN, Hamm HE, Zent R, Breyer RM. Natarajan C, et al. Among authors: breyer rm. Mol Pharmacol. 2013 Jan;83(1):206-16. doi: 10.1124/mol.112.080473. Epub 2012 Oct 18. Mol Pharmacol. 2013. PMID: 23087260 Free PMC article.

8

Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo.

Macias-Perez IM, Zent R, Carmosino M, Breyer MD, Breyer RM, Pozzi A. Macias-Perez IM, et al. Among authors: breyer rm, breyer md. J Biol Chem. 2008 May 2;283(18):12538-45. doi: 10.1074/jbc.M800105200. Epub 2008 Jan 29. J Biol Chem. 2008. PMID: 18230618 Free PMC article.

9

The second extracellular loop of the prostaglandin EP3 receptor is an essential determinant of ligand selectivity.

Audoly L, Breyer RM. Audoly L, et al. Among authors: breyer rm. J Biol Chem. 1997 May 23;272(21):13475-8. doi: 10.1074/jbc.272.21.13475. J Biol Chem. 1997. PMID: 9153190 Free article.

10

Correction to CHOBIMALT: A Cholesterol-Based Detergent.

Howell SC, Fraser NJ, Mittal R, Huang L, Travis B, Breyer RM, Sanders CR. Howell SC, et al. Among authors: breyer rm. Biochemistry. 2013 Jan 15;52(2):445. doi: 10.1021/bi3017203. Epub 2013 Jan 4. Biochemistry. 2013. PMID: 23289860 Free PMC article. No abstract available.

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