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ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
Blood. 2011 Mar 3;117(9):2658-67. doi: 10.1182/blood-2010-03-275347. Epub 2011 Jan 11.
Blood. 2011.
PMID: 21224468
Free article.
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
Krapf G, Kaindl U, Kilbey A, Fuka G, Inthal A, Joas R, Mann G, Neil JC, Haas OA, Panzer-Grümayer ER.
Krapf G, et al. Among authors: fuka g.
Oncogene. 2010 Jun 3;29(22):3307-12. doi: 10.1038/onc.2010.53. Epub 2010 Mar 1.
Oncogene. 2010.
PMID: 20190817
Free PMC article.
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Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts.
Fuka G, Kantner HP, Grausenburger R, Inthal A, Bauer E, Krapf G, Kaindl U, Kauer M, Dworzak MN, Stoiber D, Haas OA, Panzer-Grümayer R.
Fuka G, et al.
Leukemia. 2012 May;26(5):927-33. doi: 10.1038/leu.2011.322. Epub 2011 Nov 18.
Leukemia. 2012.
PMID: 22094587
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Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia.
Inthal A, Krapf G, Beck D, Joas R, Kauer MO, Orel L, Fuka G, Mann G, Panzer-Grümayer ER.
Inthal A, et al. Among authors: fuka g.
Clin Cancer Res. 2008 Nov 15;14(22):7196-204. doi: 10.1158/1078-0432.CCR-07-5051.
Clin Cancer Res. 2008.
PMID: 19010836
Free PMC article.
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The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression.
Fuka G, Kauer M, Kofler R, Haas OA, Panzer-Grümayer R.
Fuka G, et al.
PLoS One. 2011;6(10):e26348. doi: 10.1371/journal.pone.0026348. Epub 2011 Oct 20.
PLoS One. 2011.
PMID: 22028862
Free PMC article.
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Evaluation of multiplex ligation dependent probe amplification (MLPA) for identification of acute lymphoblastic leukemia with an intrachromosomal amplification of chromosome 21 (iAMP21) in a Brazilian population.
Fuka G, Farias-Vieira TM, Hummel L, Blunck CB, Santoro JC, Terra-Granado E, Barbosa TC, Emerenciano M, Pombo-de-Oliveira MS.
Fuka G, et al.
Mol Cytogenet. 2015 Jun 10;8:35. doi: 10.1186/s13039-015-0147-2. eCollection 2015.
Mol Cytogenet. 2015.
PMID: 26060508
Free PMC article.
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