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NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice.
Carnesecchi S, Deffert C, Pagano A, Garrido-Urbani S, Métrailler-Ruchonnet I, Schäppi M, Donati Y, Matthay MA, Krause KH, Barazzone Argiroffo C. Carnesecchi S, et al. Among authors: donati y. Am J Respir Crit Care Med. 2009 Nov 15;180(10):972-81. doi: 10.1164/rccm.200902-0296OC. Epub 2009 Aug 6. Am J Respir Crit Care Med. 2009. PMID: 19661248 Free PMC article.
A key role for NOX4 in epithelial cell death during development of lung fibrosis.
Carnesecchi S, Deffert C, Donati Y, Basset O, Hinz B, Preynat-Seauve O, Guichard C, Arbiser JL, Banfi B, Pache JC, Barazzone-Argiroffo C, Krause KH. Carnesecchi S, et al. Among authors: donati y. Antioxid Redox Signal. 2011 Aug 1;15(3):607-19. doi: 10.1089/ars.2010.3829. Epub 2011 May 25. Antioxid Redox Signal. 2011. PMID: 21391892 Free PMC article.
NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of acute respiratory distress syndrome.
Carnesecchi S, Dunand-Sauthier I, Zanetti F, Singovski G, Deffert C, Donati Y, Cagarelli T, Pache JC, Krause KH, Reith W, Barazzone-Argiroffo C. Carnesecchi S, et al. Among authors: donati y. Int J Clin Exp Pathol. 2014 Jan 15;7(2):537-51. eCollection 2014. Int J Clin Exp Pathol. 2014. PMID: 24551274 Free PMC article.
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