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Effect of Moderate Red Wine versus Vodka Consumption on Inflammatory Markers Related to Cardiovascular Disease Risk: A Randomized Crossover Study.
Wotherspoon A, Elshahat S, McAlinden N, Dean K, Young IS, Sharpe PC, Blankenburg S, Patterson CC, McKinley MC, Evans A, Woodside JV. Wotherspoon A, et al. Among authors: sharpe pc. J Am Coll Nutr. 2020 Aug;39(6):495-500. doi: 10.1080/07315724.2019.1695234. Epub 2019 Nov 26. J Am Coll Nutr. 2020. PMID: 31770081 Clinical Trial.
Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization.
Al-Eisawi Z, Stefani C, Jansson PJ, Arvind A, Sharpe PC, Basha MT, Iskander GM, Kumar N, Kovacevic Z, Lane DJ, Sahni S, Bernhardt PV, Richardson DR, Kalinowski DS. Al-Eisawi Z, et al. Among authors: sharpe pc. J Med Chem. 2016 Jan 14;59(1):294-312. doi: 10.1021/acs.jmedchem.5b01399. Epub 2015 Dec 31. J Med Chem. 2016. PMID: 26645570
Electrochemically mediated enantioselective reduction of chiral sulfoxides.
Chen KI, Challinor VL, Kielmann L, Sharpe PC, De Voss JJ, Kappler U, McEwan AG, Bernhardt PV. Chen KI, et al. Among authors: sharpe pc. J Biol Inorg Chem. 2015 Mar;20(2):395-402. doi: 10.1007/s00775-014-1215-5. Epub 2014 Nov 20. J Biol Inorg Chem. 2015. PMID: 25410832
Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.
Lovejoy DB, Sharp DM, Seebacher N, Obeidy P, Prichard T, Stefani C, Basha MT, Sharpe PC, Jansson PJ, Kalinowski DS, Bernhardt PV, Richardson DR. Lovejoy DB, et al. Among authors: sharpe pc. J Med Chem. 2012 Aug 23;55(16):7230-44. doi: 10.1021/jm300768u. Epub 2012 Aug 3. J Med Chem. 2012. PMID: 22861499
Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
Quach P, Gutierrez E, Basha MT, Kalinowski DS, Sharpe PC, Lovejoy DB, Bernhardt PV, Jansson PJ, Richardson DR. Quach P, et al. Among authors: sharpe pc. Mol Pharmacol. 2012 Jul;82(1):105-14. doi: 10.1124/mol.112.078964. Epub 2012 Apr 16. Mol Pharmacol. 2012. PMID: 22508546
64 results