Lovejoy DB - Search Results

1

The medicinal chemistry of novel iron chelators for the treatment of cancer.

Kovacevic Z, Kalinowski DS, Lovejoy DB, Yu Y, Suryo Rahmanto Y, Sharpe PC, Bernhardt PV, Richardson DR. Kovacevic Z, et al. Among authors: lovejoy db. Curr Top Med Chem. 2011;11(5):483-99. doi: 10.2174/156802611794785190. Curr Top Med Chem. 2011. PMID: 21192781 Review.

2

Novel "hybrid" iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells.

Lovejoy DB, Richardson DR. Lovejoy DB, et al. Blood. 2002 Jul 15;100(2):666-76. doi: 10.1182/blood.v100.2.666. Blood. 2002. PMID: 12091363 Free article.

3

Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

Chaston TB, Lovejoy DB, Watts RN, Richardson DR. Chaston TB, et al. Among authors: lovejoy db. Clin Cancer Res. 2003 Jan;9(1):402-14. Clin Cancer Res. 2003. PMID: 12538494

4

Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

Yuan J, Lovejoy DB, Richardson DR. Yuan J, et al. Among authors: lovejoy db. Blood. 2004 Sep 1;104(5):1450-8. doi: 10.1182/blood-2004-03-0868. Epub 2004 May 18. Blood. 2004. PMID: 15150082 Free article.

5

PCTH: a novel orally active chelator for the treatment of iron overload disease.

Lovejoy DB, Kalinowski D, Bernhardt PV, Richardson DR. Lovejoy DB, et al. Hemoglobin. 2006;30(1):93-104. doi: 10.1080/03630260500455367. Hemoglobin. 2006. PMID: 16540421 Review.

6

Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.

Richardson DR, Sharpe PC, Lovejoy DB, Senaratne D, Kalinowski DS, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: lovejoy db. J Med Chem. 2006 Nov 2;49(22):6510-21. doi: 10.1021/jm0606342. J Med Chem. 2006. PMID: 17064069

7

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

Yu Y, Wong J, Lovejoy DB, Kalinowski DS, Richardson DR. Yu Y, et al. Among authors: lovejoy db. Clin Cancer Res. 2006 Dec 1;12(23):6876-83. doi: 10.1158/1078-0432.CCR-06-1954. Clin Cancer Res. 2006. PMID: 17145804 Review.

8

Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.

Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR. Kalinowski DS, et al. Among authors: lovejoy db. J Med Chem. 2007 Jul 26;50(15):3716-29. doi: 10.1021/jm070445z. Epub 2007 Jun 30. J Med Chem. 2007. PMID: 17602603

9

Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.

Bernhardt PV, Sharpe PC, Islam M, Lovejoy DB, Kalinowski DS, Richardson DR. Bernhardt PV, et al. Among authors: lovejoy db. J Med Chem. 2009 Jan 22;52(2):407-15. doi: 10.1021/jm801012z. J Med Chem. 2009. PMID: 19090766

10

2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.

Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: lovejoy db. J Med Chem. 2009 Mar 12;52(5):1459-70. doi: 10.1021/jm801585u. J Med Chem. 2009. PMID: 19216562

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