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Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Bioorg Med Chem Lett. 2011 Jan 1;21(1):97-101. doi: 10.1016/j.bmcl.2010.11.060. Epub 2010 Nov 19.
Bioorg Med Chem Lett. 2011.
PMID: 21145740
Identification of substituted 6-amino-4-phenyltetrahydroquinoline derivatives: potent antagonists for the follicle-stimulating hormone receptor.
van Straten NC, van Berkel TH, Demont DR, Karstens WJ, Merkx R, Oosterom J, Schulz J, van Someren RG, Timmers CM, van Zandvoort PM.
van Straten NC, et al.
J Med Chem. 2005 Mar 24;48(6):1697-700. doi: 10.1021/jm049676l.
J Med Chem. 2005.
PMID: 15771412
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Small molecule biaryl FSH receptor agonists. Part 1: Lead discovery via encoded combinatorial synthesis.
Guo T, Adang AE, Dolle RE, Dong G, Fitzpatrick D, Geng P, Ho KK, Kultgen SG, Liu R, McDonald E, McGuinness BF, Saionz KW, Valenzano KJ, van Straten NC, Xie D, Webb ML.
Guo T, et al. Among authors: van straten nc.
Bioorg Med Chem Lett. 2004 Apr 5;14(7):1713-6. doi: 10.1016/j.bmcl.2004.01.042.
Bioorg Med Chem Lett. 2004.
PMID: 15026056
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Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis.
Guo T, Adang AE, Dong G, Fitzpatrick D, Geng P, Ho KK, Jibilian CH, Kultgen SG, Liu R, McDonald E, Saionz KW, Valenzano KJ, van Straten NC, Xie D, Webb ML.
Guo T, et al. Among authors: van straten nc.
Bioorg Med Chem Lett. 2004 Apr 5;14(7):1717-20. doi: 10.1016/j.bmcl.2004.01.043.
Bioorg Med Chem Lett. 2004.
PMID: 15026057
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The first orally active low molecular weight agonists for the LH receptor: thienopyr(im)idines with therapeutic potential for ovulation induction.
van Straten NC, Schoonus-Gerritsma GG, van Someren RG, Draaijer J, Adang AE, Timmers CM, Hanssen RG, van Boeckel CA.
van Straten NC, et al.
Chembiochem. 2002 Oct 4;3(10):1023-6. doi: 10.1002/1439-7633(20021004)3:10<1023::AID-CBIC1023>3.0.CO;2-9.
Chembiochem. 2002.
PMID: 12362369
No abstract available.
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Evidence for the involvement of a small subregion of the endoplasmic reticulum in the inositol trisphosphate receptor-induced activation of Ca2+ inflow in rat hepatocytes.
Gregory RB, Wilcox RA, Berven LA, van Straten NC, van der Marel GA, van Boom JH, Barritt GJ.
Gregory RB, et al. Among authors: van straten nc.
Biochem J. 1999 Jul 15;341 ( Pt 2)(Pt 2):401-8.
Biochem J. 1999.
PMID: 10393099
Free PMC article.
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Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy.
Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW.
Beecroft MD, et al. Among authors: van straten nc.
Mol Pharmacol. 1999 Jan;55(1):109-17. doi: 10.1124/mol.55.1.109.
Mol Pharmacol. 1999.
PMID: 9882704
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Design and In Vitro Validation of an Orthopaedic Drill Guide for Femoral Stem Revision in Total Hip Arthroplasty.
Klok JW, Groenewegen J, Temmerman O, Van Straten N, Van Straten B, Dankelman J, Horeman T.
Klok JW, et al. Among authors: van straten n.
IEEE J Transl Eng Health Med. 2024 Feb 12;12:340-347. doi: 10.1109/JTEHM.2024.3365300. eCollection 2024.
IEEE J Transl Eng Health Med. 2024.
PMID: 38606389
Free PMC article.
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