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Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein.
Balducci C, Beeg M, Stravalaci M, Bastone A, Sclip A, Biasini E, Tapella L, Colombo L, Manzoni C, Borsello T, Chiesa R, Gobbi M, Salmona M, Forloni G. Balducci C, et al. Among authors: gobbi m. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2295-300. doi: 10.1073/pnas.0911829107. Epub 2010 Jan 19. Proc Natl Acad Sci U S A. 2010. PMID: 20133875 Free PMC article.
New method based on capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) to monitor interaction between nanoparticles and the amyloid-β peptide.
Brambilla D, Verpillot R, Taverna M, De Kimpe L, Le Droumaguet B, Nicolas J, Canovi M, Gobbi M, Mantegazza F, Salmona M, Nicolas V, Scheper W, Couvreur P, Andrieux K. Brambilla D, et al. Among authors: gobbi m. Anal Chem. 2010 Dec 15;82(24):10083-9. doi: 10.1021/ac102045x. Epub 2010 Nov 18. Anal Chem. 2010. PMID: 21086977
The binding affinity of anti-Aβ1-42 MAb-decorated nanoliposomes to Aβ1-42 peptides in vitro and to amyloid deposits in post-mortem tissue.
Canovi M, Markoutsa E, Lazar AN, Pampalakis G, Clemente C, Re F, Sesana S, Masserini M, Salmona M, Duyckaerts C, Flores O, Gobbi M, Antimisiaris SG. Canovi M, et al. Among authors: gobbi m. Biomaterials. 2011 Aug;32(23):5489-97. doi: 10.1016/j.biomaterials.2011.04.020. Epub 2011 May 6. Biomaterials. 2011. PMID: 21529932
PEGylated nanoparticles bind to and alter amyloid-beta peptide conformation: toward engineering of functional nanomedicines for Alzheimer's disease.
Brambilla D, Verpillot R, Le Droumaguet B, Nicolas J, Taverna M, Kóňa J, Lettiero B, Hashemi SH, De Kimpe L, Canovi M, Gobbi M, Nicolas V, Scheper W, Moghimi SM, Tvaroška I, Couvreur P, Andrieux K. Brambilla D, et al. Among authors: gobbi m. ACS Nano. 2012 Jul 24;6(7):5897-908. doi: 10.1021/nn300489k. Epub 2012 Jun 19. ACS Nano. 2012. PMID: 22686577
741 results