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Protection Afforded by Fluoroquinolones in Animal Models of Respiratory Infections with Bacillus anthracis, Yersinia pestis, and Francisella tularensis.
Open Microbiol J. 2010 Jun 3;4:34-46. doi: 10.2174/1874285801004010034.
Open Microbiol J. 2010.
PMID: 21127743
Free PMC article.
Human monoclonal antibody AVP-21D9 to protective antigen reduces dissemination of the Bacillus anthracis Ames strain from the lungs in a rabbit model.
Peterson JW, Comer JE, Baze WB, Noffsinger DM, Wenglikowski A, Walberg KG, Hardcastle J, Pawlik J, Bush K, Taormina J, Moen S, Thomas J, Chatuev BM, Sower L, Chopra AK, Stanberry LR, Sawada R, Scholz WW, Sircar J.
Peterson JW, et al. Among authors: pawlik j.
Infect Immun. 2007 Jul;75(7):3414-24. doi: 10.1128/IAI.00352-07. Epub 2007 Apr 23.
Infect Immun. 2007.
PMID: 17452469
Free PMC article.
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Testing the efficacy and toxicity of adenylyl cyclase inhibitors against enteric pathogens using in vitro and in vivo models of infection.
Moen ST, Blumentritt CA, Slater TM, Patel SD, Tutt CB, Estrella-Jimenez ME, Pawlik J, Sower L, Popov VL, Schein CH, Gilbertson SR, Peterson JW, Torres AG.
Moen ST, et al.
Infect Immun. 2010 Apr;78(4):1740-9. doi: 10.1128/IAI.01114-09. Epub 2010 Feb 1.
Infect Immun. 2010.
PMID: 20123712
Free PMC article.
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Synthesis and screening of small molecule inhibitors of anthrax edema factor.
Jimenez ME, Bush K, Pawlik J, Sower L, Peterson JW, Gilbertson SR.
Jimenez ME, et al.
Bioorg Med Chem Lett. 2008 Jul 15;18(14):4215-8. doi: 10.1016/j.bmcl.2008.05.059. Epub 2008 May 20.
Bioorg Med Chem Lett. 2008.
PMID: 18539457
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Structure-based redesign of an edema toxin inhibitor.
Chen D, Ma L, Kanalas JJ, Gao J, Pawlik J, Jimenez ME, Walter MA, Peterson JW, Gilbertson SR, Schein CH.
Chen D, et al.
Bioorg Med Chem. 2012 Jan 1;20(1):368-76. doi: 10.1016/j.bmc.2011.10.091. Epub 2011 Nov 16.
Bioorg Med Chem. 2012.
PMID: 22154558
Free PMC article.
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Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi.
Evans SE, Scott BL, Clement CG, Larson DT, Kontoyiannis D, Lewis RE, Lasala PR, Pawlik J, Peterson JW, Chopra AK, Klimpel G, Bowden G, Höök M, Xu Y, Tuvim MJ, Dickey BF.
Evans SE, et al.
Am J Respir Cell Mol Biol. 2010 Jan;42(1):40-50. doi: 10.1165/rcmb.2008-0260OC. Epub 2009 Mar 27.
Am J Respir Cell Mol Biol. 2010.
PMID: 19329554
Free PMC article.
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Recombinant anthrax toxin receptor-Fc fusion proteins produced in plants protect rabbits against inhalational anthrax.
Wycoff KL, Belle A, Deppe D, Schaefer L, Maclean JM, Haase S, Trilling AK, Liu S, Leppla SH, Geren IN, Pawlik J, Peterson JW.
Wycoff KL, et al.
Antimicrob Agents Chemother. 2011 Jan;55(1):132-9. doi: 10.1128/AAC.00592-10. Epub 2010 Oct 18.
Antimicrob Agents Chemother. 2011.
PMID: 20956592
Free PMC article.
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