Florent JC - Search Results

1

Domino approach to 2-aroyltrimethoxyindoles as novel heterocyclic combretastatin A4 analogues.

Arthuis M, Pontikis R, Chabot GG, Quentin L, Scherman D, Florent JC. Arthuis M, et al. Among authors: florent jc. Eur J Med Chem. 2011 Jan;46(1):95-100. doi: 10.1016/j.ejmech.2010.10.018. Epub 2010 Nov 10. Eur J Med Chem. 2011. PMID: 21112130

2

Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.

Kaffy J, Pontikis R, Florent JC, Monneret C. Kaffy J, et al. Among authors: florent jc. Org Biomol Chem. 2005 Jul 21;3(14):2657-60. doi: 10.1039/b505955k. Epub 2005 Jun 21. Org Biomol Chem. 2005. PMID: 15999202

3

Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation.

Kaffy J, Pontikis R, Carrez D, Croisy A, Monneret C, Florent JC. Kaffy J, et al. Among authors: florent jc. Bioorg Med Chem. 2006 Jun 15;14(12):4067-77. doi: 10.1016/j.bmc.2006.02.001. Epub 2006 Feb 28. Bioorg Med Chem. 2006. PMID: 16510288

4

Synthesis and biological evaluation of cis-locked vinylogous combretastatin-A4 analogues: derivatives with a cyclopropyl-vinyl or a cyclopropyl-amide bridge.

Ty N, Kaffy J, Arrault A, Thoret S, Pontikis R, Dubois J, Morin-Allory L, Florent JC. Ty N, et al. Among authors: florent jc. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1318-22. doi: 10.1016/j.bmcl.2009.01.062. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19211248

5

Palladium-catalyzed domino C,N-coupling/carbonylation/Suzuki coupling reaction: an efficient synthesis of 2-aroyl-/heteroaroylindoles.

Arthuis M, Pontikis R, Florent JC. Arthuis M, et al. Among authors: florent jc. Org Lett. 2009 Oct 15;11(20):4608-11. doi: 10.1021/ol901875z. Org Lett. 2009. PMID: 19764711

6

Synthesis and structure-activity relationships of constrained heterocyclic analogues of combretastatin A4.

Arthuis M, Pontikis R, Chabot GG, Seguin J, Quentin L, Bourg S, Morin-Allory L, Florent JC. Arthuis M, et al. Among authors: florent jc. ChemMedChem. 2011 Sep 5;6(9):1693-705. doi: 10.1002/cmdc.201100154. Epub 2011 Jul 5. ChemMedChem. 2011. PMID: 21732536

7

Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4.

Ty N, Pontikis R, Chabot GG, Devillers E, Quentin L, Bourg S, Florent JC. Ty N, et al. Among authors: florent jc. Bioorg Med Chem. 2013 Mar 1;21(5):1357-66. doi: 10.1016/j.bmc.2012.11.056. Epub 2012 Dec 21. Bioorg Med Chem. 2013. PMID: 23369686

8

Stereoselective synthesis of novel highly substituted isochromanone and isoquinolinone-containing exocyclic tetrasubstituted alkenes.

Arthuis M, Pontikis R, Florent JC. Arthuis M, et al. Among authors: florent jc. J Org Chem. 2009 Mar 6;74(5):2234-7. doi: 10.1021/jo802729s. J Org Chem. 2009. PMID: 19199667

9

Synthesis and antitumor activity of isodoxorubicin analogues.

Florent JC, Gaudel G, Monneret C, Hoffmann D, Kraemer HP. Florent JC, et al. J Med Chem. 1993 May 14;36(10):1364-8. doi: 10.1021/jm00062a008. J Med Chem. 1993. PMID: 8496904

10

Prodrugs of anthracyclines for use in antibody-directed enzyme prodrug therapy.

Florent JC, Dong X, Gaudel G, Mitaku S, Monneret C, Gesson JP, Jacquesy JC, Mondon M, Renoux B, Andrianomenjanahary S, Michel S, Koch M, Tillequin F, Gerken M, Czech J, Straub R, Bosslet K. Florent JC, et al. J Med Chem. 1998 Sep 10;41(19):3572-81. doi: 10.1021/jm970589l. J Med Chem. 1998. PMID: 9733483

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