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The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties.
Esposito G, Ricagno S, Corazza A, Rennella E, Gümral D, Mimmi MC, Betto E, Pucillo CE, Fogolari F, Viglino P, Raimondi S, Giorgetti S, Bolognesi B, Merlini G, Stoppini M, Bolognesi M, Bellotti V. Esposito G, et al. Among authors: merlini g. J Mol Biol. 2008 May 9;378(4):887-97. doi: 10.1016/j.jmb.2008.03.002. Epub 2008 Mar 8. J Mol Biol. 2008. PMID: 18395224
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen.
Giorgetti S, Rossi A, Mangione P, Raimondi S, Marini S, Stoppini M, Corazza A, Viglino P, Esposito G, Cetta G, Merlini G, Bellotti V. Giorgetti S, et al. Among authors: merlini g. Protein Sci. 2005 Mar;14(3):696-702. doi: 10.1110/ps.041194005. Epub 2005 Feb 2. Protein Sci. 2005. PMID: 15689502 Free PMC article.
Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis.
Lavatelli F, Mazzini G, Ricagno S, Iavarone F, Rognoni P, Milani P, Nuvolone M, Swuec P, Caminito S, Tasaki M, Chaves-Sanjuan A, Urbani A, Merlini G, Palladini G. Lavatelli F, et al. Among authors: merlini g. J Biol Chem. 2020 Dec 4;295(49):16572-16584. doi: 10.1074/jbc.RA120.013461. Epub 2020 Sep 20. J Biol Chem. 2020. PMID: 32952127 Free PMC article.
Proteomics of beta2-microglobulin amyloid fibrils.
Stoppini M, Mangione P, Monti M, Giorgetti S, Marchese L, Arcidiaco P, Verga L, Segagni S, Pucci P, Merlini G, Bellotti V. Stoppini M, et al. Among authors: merlini g. Biochim Biophys Acta. 2005 Nov 10;1753(1):23-33. doi: 10.1016/j.bbapap.2005.07.019. Epub 2005 Aug 15. Biochim Biophys Acta. 2005. PMID: 16154394 Review.
[No title available]
[No authors listed] [No authors listed] PMID: 33453895
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.
Giorgetti S, Stoppini M, Tennent GA, Relini A, Marchese L, Raimondi S, Monti M, Marini S, Østergaard O, Heegaard NH, Pucci P, Esposito G, Merlini G, Bellotti V. Giorgetti S, et al. Among authors: merlini g. Protein Sci. 2007 Feb;16(2):343-9. doi: 10.1110/ps.062563507. Protein Sci. 2007. PMID: 17242436 Free PMC article.
Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I.
Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM, Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L, Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM, Piccoli R, Bellotti V. Raimondi S, et al. Among authors: merlini g. J Mol Biol. 2011 Apr 1;407(3):465-76. doi: 10.1016/j.jmb.2011.01.044. Epub 2011 Feb 4. J Mol Biol. 2011. PMID: 21296086
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains.
Maritan M, Romeo M, Oberti L, Sormanni P, Tasaki M, Russo R, Ambrosetti A, Motta P, Rognoni P, Mazzini G, Barbiroli A, Palladini G, Vendruscolo M, Diomede L, Bolognesi M, Merlini G, Lavatelli F, Ricagno S. Maritan M, et al. Among authors: merlini g. J Mol Biol. 2020 Feb 14;432(4):845-860. doi: 10.1016/j.jmb.2019.12.015. Epub 2019 Dec 24. J Mol Biol. 2020. PMID: 31874151 Free article.
613 results