Leeder JS - Search Results

1

Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.

Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM. Feng Q, et al. Among authors: leeder js. Mol Genet Metab. 2011 Feb;102(2):126-33. doi: 10.1016/j.ymgme.2010.10.010. Epub 2010 Oct 21. Mol Genet Metab. 2011. PMID: 21093336 Free PMC article.

2

Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects.

Adjei AA, Gaedigk A, Simon SD, Weinshilboum RM, Leeder JS. Adjei AA, et al. Among authors: leeder js. Birth Defects Res A Clin Mol Teratol. 2008 Mar;82(3):155-65. doi: 10.1002/bdra.20535. Birth Defects Res A Clin Mol Teratol. 2008. PMID: 18232020

3

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.

Wang D, Poi MJ, Sun X, Gaedigk A, Leeder JS, Sadee W. Wang D, et al. Among authors: leeder js. Hum Mol Genet. 2014 Jan 1;23(1):268-78. doi: 10.1093/hmg/ddt417. Epub 2013 Aug 28. Hum Mol Genet. 2014. PMID: 23985325 Free PMC article.

4

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.

Hicks JK, Bishop JR, Sangkuhl K, Müller DJ, Ji Y, Leckband SG, Leeder JS, Graham RL, Chiulli DL, LLerena A, Skaar TC, Scott SA, Stingl JC, Klein TE, Caudle KE, Gaedigk A; Clinical Pharmacogenetics Implementation Consortium. Hicks JK, et al. Among authors: leeder js. Clin Pharmacol Ther. 2015 Aug;98(2):127-34. doi: 10.1002/cpt.147. Epub 2015 Jun 29. Clin Pharmacol Ther. 2015. PMID: 25974703 Free PMC article. Review.

5

Ontogeny-related pharmacogene changes in the pediatric liver transcriptome.

Meier R, Bi C, Gaedigk R, Heruth DP, Ye SQ, Leeder JS, Fridley BL. Meier R, et al. Among authors: leeder js. Pharmacogenet Genomics. 2018 Mar;28(3):86-94. doi: 10.1097/FPC.0000000000000326. Pharmacogenet Genomics. 2018. PMID: 29360682 Free PMC article.

6

Ontogeny Related Changes in the Pediatric Liver Metabolome.

Wilson CM, Li Q, Gaedigk R, Bi C, de Wildt SN, Leeder JS, Fridley BL. Wilson CM, et al. Among authors: leeder js. Front Pediatr. 2020 Sep 29;8:549. doi: 10.3389/fped.2020.00549. eCollection 2020. Front Pediatr. 2020. PMID: 33117761 Free PMC article.

7

Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.

Gaedigk A, Bhathena A, Ndjountché L, Pearce RE, Abdel-Rahman SM, Alander SW, Bradford LD, Rogan PK, Leeder JS. Gaedigk A, et al. Among authors: leeder js. Pharmacogenomics J. 2005;5(3):173-82. doi: 10.1038/sj.tpj.6500305. Pharmacogenomics J. 2005. PMID: 15768052 Free PMC article.

8

CYP2D7 splice variants in human liver and brain: does CYP2D7 encode functional protein?

Gaedigk A, Gaedigk R, Leeder JS. Gaedigk A, et al. Among authors: leeder js. Biochem Biophys Res Commun. 2005 Nov 4;336(4):1241-50. doi: 10.1016/j.bbrc.2005.08.255. Biochem Biophys Res Commun. 2005. PMID: 16169517

9

Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression.

Vyhlidal CA, Gaedigk R, Leeder JS. Vyhlidal CA, et al. Among authors: leeder js. Drug Metab Dispos. 2006 Jan;34(1):131-7. doi: 10.1124/dmd.105.005967. Epub 2005 Oct 21. Drug Metab Dispos. 2006. PMID: 16243958

10

The role of CYP3A4 mRNA transcript with shortened 3'-untranslated region in hepatocyte differentiation, liver development, and response to drug induction.

Li D, Gaedigk R, Hart SN, Leeder JS, Zhong XB. Li D, et al. Among authors: leeder js. Mol Pharmacol. 2012 Jan;81(1):86-96. doi: 10.1124/mol.111.074393. Epub 2011 Oct 13. Mol Pharmacol. 2012. PMID: 21998292 Free PMC article.

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