Commandeur JN - Search Results

1

Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone.

Reinen J, Kalma LL, Begheijn S, Heus F, Commandeur JN, Vermeulen NP. Reinen J, et al. Among authors: commandeur jn. Xenobiotica. 2011 Jan;41(1):59-70. doi: 10.3109/00498254.2010.525762. Epub 2010 Nov 18. Xenobiotica. 2011. PMID: 21087115

2

Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.

Commandeur JN, Boogaard PJ, Mulder GJ, Vermeulen NP. Commandeur JN, et al. Arch Toxicol. 1991;65(5):373-80. doi: 10.1007/BF02284259. Arch Toxicol. 1991. PMID: 1929851

3

Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat.

Commandeur JN, Vermeulen NP. Commandeur JN, et al. Chem Res Toxicol. 1990 May-Jun;3(3):212-8. doi: 10.1021/tx00015a005. Chem Res Toxicol. 1990. PMID: 1966701

4

Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.

Commandeur JN, Stijntjes GJ, Wijngaard J, Vermeulen NP. Commandeur JN, et al. Biochem Pharmacol. 1991 Jun 21;42(1):31-8. doi: 10.1016/0006-2952(91)90677-w. Biochem Pharmacol. 1991. PMID: 2069595

5

Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review.

Commandeur JN, Vermeulen NP. Commandeur JN, et al. Chem Res Toxicol. 1990 May-Jun;3(3):171-94. doi: 10.1021/tx00015a001. Chem Res Toxicol. 1990. PMID: 2131829 Review. No abstract available.

6

Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney. Uptake of the conjugates and activation to toxic metabolites.

Boogaard PJ, Commandeur JN, Mulder GJ, Vermeulen NP, Nagelkerke JF. Boogaard PJ, et al. Among authors: commandeur jn. Biochem Pharmacol. 1989 Nov 1;38(21):3731-41. doi: 10.1016/0006-2952(89)90579-0. Biochem Pharmacol. 1989. PMID: 2597169

7

Bioactivation of the cysteine-S-conjugate and mercapturic acid of tetrafluoroethylene to acylating reactive intermediates in the rat: dependence of activation and deactivation activities on acetyl coenzyme A availability.

Commandeur JN, De Kanter FJ, Vermeulen NP. Commandeur JN, et al. Mol Pharmacol. 1989 Oct;36(4):654-63. Mol Pharmacol. 1989. PMID: 2811861

8

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms.

Commandeur JN, Brakenhoff JP, De Kanter FJ, Vermeulen NP. Commandeur JN, et al. Biochem Pharmacol. 1988 Dec 1;37(23):4495-504. doi: 10.1016/0006-2952(88)90665-x. Biochem Pharmacol. 1988. PMID: 3202890

9

Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation.

Commandeur JN, Oostendorp RA, Schoofs PR, Xu B, Vermeulen NP. Commandeur JN, et al. Biochem Pharmacol. 1987 Dec 15;36(24):4229-37. doi: 10.1016/0006-2952(87)90663-0. Biochem Pharmacol. 1987. PMID: 3689448

10

A predictive substrate model for rat glutathione S-transferase 4-4.

de Groot MJ, van der Aar EM, Nieuwenhuizen PJ, van der Plas RM, Donné-Op den Kelder GM, Commandeur JN, Vermeulen NP. de Groot MJ, et al. Among authors: commandeur jn. Chem Res Toxicol. 1995 Jul-Aug;8(5):649-58. doi: 10.1021/tx00047a004. Chem Res Toxicol. 1995. PMID: 7548747

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