Roell MK - Search Results

1

XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases.

Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L. Owyang AM, et al. Among authors: roell mk. MAbs. 2011 Jan-Feb;3(1):49-60. doi: 10.4161/mabs.3.1.13989. Epub 2011 Jan 1. MAbs. 2011. PMID: 21048425 Free PMC article.

2

Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.

Roell MK, Issafras H, Bauer RJ, Michelson KS, Mendoza N, Vanegas SI, Gross LM, Larsen PD, Bedinger DH, Bohmann DJ, Nonet GH, Liu N, Lee SR, Handa M, Kantak SS, Horwitz AH, Hunter JJ, Owyang AM, Mirza AM, Corbin JA, White ML. Roell MK, et al. J Biol Chem. 2010 Jul 2;285(27):20607-14. doi: 10.1074/jbc.M110.115790. Epub 2010 Apr 21. J Biol Chem. 2010. PMID: 20410301 Free PMC article.

3

Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1β antibody with differential receptor-modulating properties.

Issafras H, Corbin JA, Goldfine ID, Roell MK. Issafras H, et al. Among authors: roell mk. J Pharmacol Exp Ther. 2014 Jan;348(1):202-15. doi: 10.1124/jpet.113.205443. Epub 2013 Nov 5. J Pharmacol Exp Ther. 2014. PMID: 24194526 Free PMC article.

4

Development of XPA067.06, a potent high affinity human anti-gastrin monoclonal antibody.

Hsu SJ, Patel A, Larsen PD, Bohmann DJ, Bauer RJ, Ma JK, Masat L, Roell M, Babuka SJ, Hansen RK, White M, Haak-Frendscho M. Hsu SJ, et al. Biochem Pharmacol. 2008 Aug 1;76(3):340-52. doi: 10.1016/j.bcp.2008.05.015. Epub 2008 May 24. Biochem Pharmacol. 2008. PMID: 18589401

5

Differential pathway coupling of the activated insulin receptor drives signaling selectivity by XMetA, an allosteric partial agonist antibody.

Bedinger DH, Goldfine ID, Corbin JA, Roell MK, Adams SH. Bedinger DH, et al. Among authors: roell mk. J Pharmacol Exp Ther. 2015 Apr;353(1):35-43. doi: 10.1124/jpet.114.221309. Epub 2015 Jan 22. J Pharmacol Exp Ther. 2015. PMID: 25613982

6

Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice.

Bedinger DH, Kieffer DA, Goldfine ID, Roell MK, Adams SH. Bedinger DH, et al. Among authors: roell mk. J Cell Biochem. 2015 Sep;116(9):2109-19. doi: 10.1002/jcb.25168. J Cell Biochem. 2015. PMID: 25808283

7

Kinetic analysis of a high-affinity antibody/antigen interaction performed by multiple Biacore users.

Katsamba PS, Navratilova I, Calderon-Cacia M, Fan L, Thornton K, Zhu M, Bos TV, Forte C, Friend D, Laird-Offringa I, Tavares G, Whatley J, Shi E, Widom A, Lindquist KC, Klakamp S, Drake A, Bohmann D, Roell M, Rose L, Dorocke J, Roth B, Luginbühl B, Myszka DG. Katsamba PS, et al. Anal Biochem. 2006 May 15;352(2):208-21. doi: 10.1016/j.ab.2006.01.034. Epub 2006 Feb 23. Anal Biochem. 2006. PMID: 16564019

8

Organization, expression and nucleotide sequence of the operon encoding R-phycoerythrin alpha and beta subunits from the red alga Polysiphonia boldii.

Roell MK, Morse DE. Roell MK, et al. Plant Mol Biol. 1993 Jan;21(1):47-58. doi: 10.1007/BF00039617. Plant Mol Biol. 1993. PMID: 8425050

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