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Epigenetic phenomena linked to diabetic complications.
Pirola L, Balcerczyk A, Okabe J, El-Osta A. Pirola L, et al. Among authors: okabe j. Nat Rev Endocrinol. 2010 Dec;6(12):665-75. doi: 10.1038/nrendo.2010.188. Epub 2010 Nov 2. Nat Rev Endocrinol. 2010. PMID: 21045787 Review.
Analysis of the IGF2/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal growth disorders.
Demars J, Shmela ME, Rossignol S, Okabe J, Netchine I, Azzi S, Cabrol S, Le Caignec C, David A, Le Bouc Y, El-Osta A, Gicquel C. Demars J, et al. Among authors: okabe j. Hum Mol Genet. 2010 Mar 1;19(5):803-14. doi: 10.1093/hmg/ddp549. Epub 2009 Dec 9. Hum Mol Genet. 2010. PMID: 20007505
NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis.
Gray SP, Di Marco E, Okabe J, Szyndralewiez C, Heitz F, Montezano AC, de Haan JB, Koulis C, El-Osta A, Andrews KL, Chin-Dusting JP, Touyz RM, Wingler K, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Gray SP, et al. Among authors: okabe j. Circulation. 2013 May 7;127(18):1888-902. doi: 10.1161/CIRCULATIONAHA.112.132159. Epub 2013 Apr 5. Circulation. 2013. PMID: 23564668
Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation.
Kitamura H, Kimura S, Shimamoto Y, Okabe J, Ito M, Miyamoto T, Naoe Y, Kikuguchi C, Meek B, Toda C, Okamoto S, Kanehira K, Hase K, Watarai H, Ishizuka M, El-Osta A, Ohara O, Miyoshi I. Kitamura H, et al. Among authors: okabe j. FASEB J. 2013 Dec;27(12):4940-53. doi: 10.1096/fj.13-233528. Epub 2013 Sep 4. FASEB J. 2013. PMID: 24005904
Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.
Jha JC, Gray SP, Barit D, Okabe J, El-Osta A, Namikoshi T, Thallas-Bonke V, Wingler K, Szyndralewiez C, Heitz F, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Jha JC, et al. Among authors: okabe j. J Am Soc Nephrol. 2014 Jun;25(6):1237-54. doi: 10.1681/ASN.2013070810. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511132 Free PMC article.
Vascular histone deacetylation by pharmacological HDAC inhibition.
Rafehi H, Balcerczyk A, Lunke S, Kaspi A, Ziemann M, Kn H, Okabe J, Khurana I, Ooi J, Khan AW, Du XJ, Chang L, Haviv I, Keating ST, Karagiannis TC, El-Osta A. Rafehi H, et al. Among authors: okabe j. Genome Res. 2014 Aug;24(8):1271-84. doi: 10.1101/gr.168781.113. Epub 2014 Apr 14. Genome Res. 2014. PMID: 24732587 Free PMC article.
87 results