El-Osta A - Search Results

1

Epigenetic phenomena linked to diabetic complications.

Pirola L, Balcerczyk A, Okabe J, El-Osta A. Pirola L, et al. Nat Rev Endocrinol. 2010 Dec;6(12):665-75. doi: 10.1038/nrendo.2010.188. Epub 2010 Nov 2. Nat Rev Endocrinol. 2010. PMID: 21045787 Review.

2

Epigenetic regulation and fetal programming.

Gicquel C, El-Osta A, Le Bouc Y. Gicquel C, et al. Best Pract Res Clin Endocrinol Metab. 2008 Feb;22(1):1-16. doi: 10.1016/j.beem.2007.07.009. Best Pract Res Clin Endocrinol Metab. 2008. PMID: 18279777 Review.

3

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia.

El-Osta A, Brasacchio D, Yao D, Pocai A, Jones PL, Roeder RG, Cooper ME, Brownlee M. El-Osta A, et al. J Exp Med. 2008 Sep 29;205(10):2409-17. doi: 10.1084/jem.20081188. Epub 2008 Sep 22. J Exp Med. 2008. PMID: 18809715 Free PMC article.

4

Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail.

Brasacchio D, Okabe J, Tikellis C, Balcerczyk A, George P, Baker EK, Calkin AC, Brownlee M, Cooper ME, El-Osta A. Brasacchio D, et al. Diabetes. 2009 May;58(5):1229-36. doi: 10.2337/db08-1666. Epub 2009 Feb 10. Diabetes. 2009. PMID: 19208907 Free PMC article.

5

Analysis of the IGF2/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal growth disorders.

Demars J, Shmela ME, Rossignol S, Okabe J, Netchine I, Azzi S, Cabrol S, Le Caignec C, David A, Le Bouc Y, El-Osta A, Gicquel C. Demars J, et al. Hum Mol Genet. 2010 Mar 1;19(5):803-14. doi: 10.1093/hmg/ddp549. Epub 2009 Dec 9. Hum Mol Genet. 2010. PMID: 20007505

6

Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms.

Tonna S, El-Osta A, Cooper ME, Tikellis C. Tonna S, et al. Nat Rev Nephrol. 2010 Jun;6(6):332-41. doi: 10.1038/nrneph.2010.55. Epub 2010 Apr 27. Nat Rev Nephrol. 2010. PMID: 20421885 Review.

7

Glycemic memory associated epigenetic changes.

Siebel AL, Fernandez AZ, El-Osta A. Siebel AL, et al. Biochem Pharmacol. 2010 Dec 15;80(12):1853-9. doi: 10.1016/j.bcp.2010.06.005. Epub 2010 Jun 19. Biochem Pharmacol. 2010. PMID: 20599797 Review.

8

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes.

Karagiannis TC, Lin AJ, Ververis K, Chang L, Tang MM, Okabe J, El-Osta A. Karagiannis TC, et al. Aging (Albany NY). 2010 Oct;2(10):659-68. doi: 10.18632/aging.100203. Aging (Albany NY). 2010. PMID: 20930262 Free PMC article.

9

Epigenetics: mechanisms and implications for diabetic complications.

Cooper ME, El-Osta A. Cooper ME, et al. Circ Res. 2010 Dec 10;107(12):1403-13. doi: 10.1161/CIRCRESAHA.110.223552. Circ Res. 2010. PMID: 21148447 Review.

10

Genetic and epigenetic events in diabetic wound healing.

Rafehi H, El-Osta A, Karagiannis TC. Rafehi H, et al. Int Wound J. 2011 Feb;8(1):12-21. doi: 10.1111/j.1742-481X.2010.00745.x. Epub 2010 Dec 16. Int Wound J. 2011. PMID: 21159125 Free PMC article. Review.

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