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A phase II trial of farnesyl protein transferase inhibitor SCH 66336, given by twice-daily oral administration, in patients with metastatic colorectal cancer refractory to 5-fluorouracil and irinotecan.
Sharma S, Kemeny N, Kelsen DP, Ilson D, O'Reilly E, Zaknoen S, Baum C, Statkevich P, Hollywood E, Zhu Y, Saltz LB. Sharma S, et al. Among authors: saltz lb. Ann Oncol. 2002 Jul;13(7):1067-71. doi: 10.1093/annonc/mdf173. Ann Oncol. 2002. PMID: 12176785 Free article. Clinical Trial.
Antibody-based therapies for colorectal cancer.
Chung KY, Saltz LB. Chung KY, et al. Oncologist. 2005 Oct;10(9):701-9. doi: 10.1634/theoncologist.10-9-701. Oncologist. 2005. PMID: 16249350 Free article. Review.
Bevacizumab 5 mg/kg can be infused safely over 10 minutes.
Reidy DL, Chung KY, Timoney JP, Park VJ, Hollywood E, Sklarin NT, Muller RJ, Saltz LB. Reidy DL, et al. Among authors: saltz lb. J Clin Oncol. 2007 Jul 1;25(19):2691-5. doi: 10.1200/JCO.2006.09.3351. J Clin Oncol. 2007. PMID: 17602073
Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study.
Saltz LB, Lenz HJ, Kindler HL, Hochster HS, Wadler S, Hoff PM, Kemeny NE, Hollywood EM, Gonen M, Quinones M, Morse M, Chen HX. Saltz LB, et al. J Clin Oncol. 2007 Oct 10;25(29):4557-61. doi: 10.1200/JCO.2007.12.0949. Epub 2007 Sep 17. J Clin Oncol. 2007. PMID: 17876013 Clinical Trial.
495 results