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A liver-derived secretory protein, selenoprotein P, causes insulin resistance.
Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S. Misu H, et al. Among authors: matsuzawa nagata n. Cell Metab. 2010 Nov 3;12(5):483-95. doi: 10.1016/j.cmet.2010.09.015. Cell Metab. 2010. PMID: 21035759 Free article.
LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance.
Lan F, Misu H, Chikamoto K, Takayama H, Kikuchi A, Mohri K, Takata N, Hayashi H, Matsuzawa-Nagata N, Takeshita Y, Noda H, Matsumoto Y, Ota T, Nagano T, Nakagen M, Miyamoto K, Takatsuki K, Seo T, Iwayama K, Tokuyama K, Matsugo S, Tang H, Saito Y, Yamagoe S, Kaneko S, Takamura T. Lan F, et al. Among authors: matsuzawa nagata n. Diabetes. 2014 May;63(5):1649-64. doi: 10.2337/db13-0728. Epub 2014 Jan 29. Diabetes. 2014. PMID: 24478397 Free article.
Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.
Ishikura K, Misu H, Kumazaki M, Takayama H, Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T. Ishikura K, et al. Among authors: matsuzawa nagata n. Diabetologia. 2014 Sep;57(9):1968-76. doi: 10.1007/s00125-014-3306-9. Epub 2014 Jul 3. Diabetologia. 2014. PMID: 24989996
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Ando H, Takamura T, Matsuzawa-Nagata N, Shima KR, Nakamura S, Kumazaki M, Kurita S, Misu H, Togawa N, Fukushima T, Fujimura A, Kaneko S. Ando H, et al. Among authors: matsuzawa nagata n. Biochem Biophys Res Commun. 2009 Mar 13;380(3):684-8. doi: 10.1016/j.bbrc.2009.01.150. Epub 2009 Jan 29. Biochem Biophys Res Commun. 2009. PMID: 19285022 Free article.
15 results