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Discovery of a novel series of cyclic urea as potent CCR5 antagonists.
Duan M, Kazmierski WM, Tallant M, Jun JH, Edelstein M, Ferris R, Todd D, Wheelan P, Xiong Z. Duan M, et al. Among authors: edelstein m. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6381-5. doi: 10.1016/j.bmcl.2011.08.096. Epub 2011 Aug 28. Bioorg Med Chem Lett. 2011. PMID: 21930378
The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?
Muniz-Medina VM, Jones S, Maglich JM, Galardi C, Hollingsworth RE, Kazmierski WM, Ferris RG, Edelstein MP, Chiswell KE, Kenakin TP. Muniz-Medina VM, et al. Among authors: edelstein mp. Mol Pharmacol. 2009 Mar;75(3):490-501. doi: 10.1124/mol.108.052555. Epub 2008 Dec 8. Mol Pharmacol. 2009. PMID: 19064629
Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis.
Bramson HN, Corona J, Davis ST, Dickerson SH, Edelstein M, Frye SV, Gampe RT Jr, Harris PA, Hassell A, Holmes WD, Hunter RN, Lackey KE, Lovejoy B, Luzzio MJ, Montana V, Rocque WJ, Rusnak D, Shewchuk L, Veal JM, Walker DH, Kuyper LF. Bramson HN, et al. Among authors: edelstein m. J Med Chem. 2001 Dec 6;44(25):4339-58. doi: 10.1021/jm010117d. J Med Chem. 2001. PMID: 11728181
Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Davis ST, Benson BG, Bramson HN, Chapman DE, Dickerson SH, Dold KM, Eberwein DJ, Edelstein M, Frye SV, Gampe RT Jr, Griffin RJ, Harris PA, Hassell AM, Holmes WD, Hunter RN, Knick VB, Lackey K, Lovejoy B, Luzzio MJ, Murray D, Parker P, Rocque WJ, Shewchuk L, Veal JM, Walker DH, Kuyper LF. Davis ST, et al. Among authors: edelstein m. Science. 2001 Jan 5;291(5501):134-7. doi: 10.1126/science.291.5501.134. Science. 2001. PMID: 11141566 Retracted.
331 results