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G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.
Ciccarelli M, Chuprun JK, Rengo G, Gao E, Wei Z, Peroutka RJ, Gold JI, Gumpert A, Chen M, Otis NJ, Dorn GW 2nd, Trimarco B, Iaccarino G, Koch WJ. Ciccarelli M, et al. Among authors: chuprun jk. Circulation. 2011 May 10;123(18):1953-62. doi: 10.1161/CIRCULATIONAHA.110.988642. Epub 2011 Apr 25. Circulation. 2011. PMID: 21518983 Free PMC article.
Endothelial S100A1 modulates vascular function via nitric oxide.
Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P. Pleger ST, et al. Among authors: chuprun jk. Circ Res. 2008 Apr 11;102(7):786-94. doi: 10.1161/CIRCRESAHA.108.172031. Epub 2008 Feb 21. Circ Res. 2008. PMID: 18292599
Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
Zhu W, Petrashevskaya N, Ren S, Zhao A, Chakir K, Gao E, Chuprun JK, Wang Y, Talan M, Dorn GW 2nd, Lakatta EG, Koch WJ, Feldman AM, Xiao RP. Zhu W, et al. Among authors: chuprun jk. Circ Res. 2012 Jan 20;110(2):265-74. doi: 10.1161/CIRCRESAHA.111.253260. Epub 2011 Dec 15. Circ Res. 2012. PMID: 22179058 Free PMC article.
39 results