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Page 1
Follow-up actions from positive results of in vitro genetic toxicity testing.
Dearfield KL, Thybaud V, Cimino MC, Custer L, Czich A, Harvey JS, Hester S, Kim JH, Kirkland D, Levy DD, Lorge E, Moore MM, Ouédraogo-Arras G, Schuler M, Suter W, Sweder K, Tarlo K, van Benthem J, van Goethem F, Witt KL. Dearfield KL, et al. Among authors: schuler m. Environ Mol Mutagen. 2011 Apr;52(3):177-204. doi: 10.1002/em.20617. Epub 2010 Oct 20. Environ Mol Mutagen. 2011. PMID: 20963811 Free article. Review.
Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.
Thybaud V, Aardema M, Clements J, Dearfield K, Galloway S, Hayashi M, Jacobson-Kram D, Kirkland D, MacGregor JT, Marzin D, Ohyama W, Schuler M, Suzuki H, Zeiger E; Expert Working Group on Hazard Identification and Risk Assessment in Relation to In Vitro Testing. Thybaud V, et al. Among authors: schuler m. Mutat Res. 2007 Feb 3;627(1):41-58. doi: 10.1016/j.mrgentox.2006.10.003. Epub 2006 Nov 27. Mutat Res. 2007. PMID: 17126066
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ. Rothfuss A, et al. Among authors: schuler m. Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21. Mutat Res. 2011. PMID: 21182982
Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus).
Galloway S, Lorge E, Aardema MJ, Eastmond D, Fellows M, Heflich R, Kirkland D, Levy DD, Lynch AM, Marzin D, Morita T, Schuler M, Speit G. Galloway S, et al. Among authors: schuler m. Mutat Res. 2011 Aug 16;723(2):77-83. doi: 10.1016/j.mrgentox.2011.01.003. Epub 2011 Jan 19. Mutat Res. 2011. PMID: 21255675
IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure-response relationships and points of departure (PoDs).
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V, Johnson GE. MacGregor JT, et al. Among authors: schuler mj. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:55-65. doi: 10.1016/j.mrgentox.2014.09.011. Epub 2014 Oct 13. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953400 Free article.
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Johnson GE, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V. MacGregor JT, et al. Among authors: schuler mj. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:66-78. doi: 10.1016/j.mrgentox.2014.10.008. Epub 2014 Oct 27. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953401 Free article.
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.
Bryce SM, Bernacki DT, Bemis JC, Spellman RA, Engel ME, Schuler M, Lorge E, Heikkinen PT, Hemmann U, Thybaud V, Wilde S, Queisser N, Sutter A, Zeller A, Guérard M, Kirkland D, Dertinger SD. Bryce SM, et al. Among authors: schuler m. Environ Mol Mutagen. 2017 Apr;58(3):146-161. doi: 10.1002/em.22083. Environ Mol Mutagen. 2017. PMID: 28370322 Free PMC article.
Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells.
Lovell DP, Fellows M, Marchetti F, Christiansen J, Elhajouji A, Hashimoto K, Kasamoto S, Li Y, Masayasu O, Moore MM, Schuler M, Smith R, Stankowski LF Jr, Tanaka J, Tanir JY, Thybaud V, Van Goethem F, Whitwell J. Lovell DP, et al. Among authors: schuler m. Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:40-50. doi: 10.1016/j.mrgentox.2017.10.006. Epub 2017 Nov 10. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29307374 Free article.
1,034 results