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Podoplanin associates with CD44 to promote directional cell migration.
Martín-Villar E, Fernández-Muñoz B, Parsons M, Yurrita MM, Megías D, Pérez-Gómez E, Jones GE, Quintanilla M. Martín-Villar E, et al. Among authors: yurrita mm. Mol Biol Cell. 2010 Dec;21(24):4387-99. doi: 10.1091/mbc.E10-06-0489. Epub 2010 Oct 20. Mol Biol Cell. 2010. PMID: 20962267 Free PMC article.
New insights into the role of podoplanin in epithelial-mesenchymal transition.
Renart J, Carrasco-Ramírez P, Fernández-Muñoz B, Martín-Villar E, Montero L, Yurrita MM, Quintanilla M. Renart J, et al. Among authors: yurrita mm. Int Rev Cell Mol Biol. 2015;317:185-239. doi: 10.1016/bs.ircmb.2015.01.009. Epub 2015 Mar 5. Int Rev Cell Mol Biol. 2015. PMID: 26008786 Review.
The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition.
Fernández-Muñoz B, Yurrita MM, Martín-Villar E, Carrasco-Ramírez P, Megías D, Renart J, Quintanilla M. Fernández-Muñoz B, et al. Among authors: yurrita mm. Int J Biochem Cell Biol. 2011 Jun;43(6):886-96. doi: 10.1016/j.biocel.2011.02.010. Epub 2011 Mar 3. Int J Biochem Cell Biol. 2011. PMID: 21376833 Free article.
Podoplanin is a substrate of presenilin-1/γ-secretase.
Yurrita MM, Fernández-Muñoz B, Del Castillo G, Martín-Villar E, Renart J, Quintanilla M. Yurrita MM, et al. Int J Biochem Cell Biol. 2014 Jan;46:68-75. doi: 10.1016/j.biocel.2013.11.016. Epub 2013 Nov 22. Int J Biochem Cell Biol. 2014. PMID: 24275092 Free article.