Hattori K - Search Results

1

Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization.

Igawa T, Ishii S, Tachibana T, Maeda A, Higuchi Y, Shimaoka S, Moriyama C, Watanabe T, Takubo R, Doi Y, Wakabayashi T, Hayasaka A, Kadono S, Miyazaki T, Haraya K, Sekimori Y, Kojima T, Nabuchi Y, Aso Y, Kawabe Y, Hattori K. Igawa T, et al. Among authors: hattori k. Nat Biotechnol. 2010 Nov;28(11):1203-7. doi: 10.1038/nbt.1691. Epub 2010 Oct 17. Nat Biotechnol. 2010. PMID: 20953198

2

Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation.

Hironiwa N, Ishii S, Kadono S, Iwayanagi Y, Mimoto F, Habu K, Igawa T, Hattori K. Hironiwa N, et al. Among authors: hattori k. MAbs. 2016;8(1):65-73. doi: 10.1080/19420862.2015.1110660. Epub 2015 Oct 23. MAbs. 2016. PMID: 26496237 Free PMC article.

3

Engineered monoclonal antibody with novel antigen-sweeping activity in vivo.

Igawa T, Maeda A, Haraya K, Tachibana T, Iwayanagi Y, Mimoto F, Higuchi Y, Ishii S, Tamba S, Hironiwa N, Nagano K, Wakabayashi T, Tsunoda H, Hattori K. Igawa T, et al. Among authors: hattori k. PLoS One. 2013 May 7;8(5):e63236. doi: 10.1371/journal.pone.0063236. Print 2013. PLoS One. 2013. PMID: 23667591 Free PMC article.

4

Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation.

Igawa T, Haraya K, Hattori K. Igawa T, et al. Among authors: hattori k. Immunol Rev. 2016 Mar;270(1):132-51. doi: 10.1111/imr.12392. Immunol Rev. 2016. PMID: 26864109 Review.

5

pH-dependent antigen-binding antibodies as a novel therapeutic modality.

Igawa T, Mimoto F, Hattori K. Igawa T, et al. Among authors: hattori k. Biochim Biophys Acta. 2014 Nov;1844(11):1943-1950. doi: 10.1016/j.bbapap.2014.08.003. Epub 2014 Aug 12. Biochim Biophys Acta. 2014. PMID: 25125373 Review.

6

Reduced elimination of IgG antibodies by engineering the variable region.

Igawa T, Tsunoda H, Tachibana T, Maeda A, Mimoto F, Moriyama C, Nanami M, Sekimori Y, Nabuchi Y, Aso Y, Hattori K. Igawa T, et al. Among authors: hattori k. Protein Eng Des Sel. 2010 May;23(5):385-92. doi: 10.1093/protein/gzq009. Epub 2010 Feb 15. Protein Eng Des Sel. 2010. PMID: 20159773

7

Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131).

Mimoto F, Katada H, Kadono S, Igawa T, Kuramochi T, Muraoka M, Wada Y, Haraya K, Miyazaki T, Hattori K. Mimoto F, et al. Among authors: hattori k. Protein Eng Des Sel. 2013 Oct;26(10):589-98. doi: 10.1093/protein/gzt022. Epub 2013 Jun 5. Protein Eng Des Sel. 2013. PMID: 23744091 Free PMC article.

8

Humanization and simultaneous optimization of monoclonal antibody.

Kuramochi T, Igawa T, Tsunoda H, Hattori K. Kuramochi T, et al. Among authors: hattori k. Methods Mol Biol. 2014;1060:123-37. doi: 10.1007/978-1-62703-586-6_7. Methods Mol Biol. 2014. PMID: 24037839

9

Crystal structure of a novel asymmetrically engineered Fc variant with improved affinity for FcγRs.

Mimoto F, Kadono S, Katada H, Igawa T, Kamikawa T, Hattori K. Mimoto F, et al. Among authors: hattori k. Mol Immunol. 2014 Mar;58(1):132-8. doi: 10.1016/j.molimm.2013.11.017. Epub 2013 Dec 14. Mol Immunol. 2014. PMID: 24334029 Free article.

10

VH/VL interface engineering to promote selective expression and inhibit conformational isomerization of thrombopoietin receptor agonist single-chain diabody.

Igawa T, Tsunoda H, Kikuchi Y, Yoshida M, Tanaka M, Koga A, Sekimori Y, Orita T, Aso Y, Hattori K, Tsuchiya M. Igawa T, et al. Among authors: hattori k. Protein Eng Des Sel. 2010 Aug;23(8):667-77. doi: 10.1093/protein/gzq034. Epub 2010 Jun 24. Protein Eng Des Sel. 2010. PMID: 20576629

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