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The production ratios of AICDε51 and Aβ42 by intramembrane proteolysis of βAPP do not always change in parallel.
Mori K, Okochi M, Tagami S, Nakayama T, Yanagida K, Kodama TS, Tatsumi S, Fujii K, Tanimukai H, Hashimoto R, Morihara T, Tanaka T, Kudo T, Funamoto S, Ihara Y, Takeda M. Mori K, et al. Among authors: takeda m. Psychogeriatrics. 2010 Sep;10(3):117-23. doi: 10.1111/j.1479-8301.2010.00330.x. Psychogeriatrics. 2010. PMID: 20860566 Free article.
Novel therapeutic strategies for neurodegenerative disease.
Tanimukai H, Kudo T, Tanaka T, Grundke-Iqbal I, Iqbal K, Takeda M. Tanimukai H, et al. Among authors: takeda m. Psychogeriatrics. 2009 Jun;9(2):103-9. doi: 10.1111/j.1479-8301.2009.00289.x. Psychogeriatrics. 2009. PMID: 19604333 Free PMC article. Review.
Destruxin E decreases Beta-amyloid generation by reducing colocalization of beta-amyloid-cleaving enzyme 1 and beta-amyloid protein precursor.
Itoh N, Okochi M, Tagami S, Nishitomi K, Nakayama T, Yanagida K, Fukumori A, Jiang J, Mori K, Hosono M, Kikuchi J, Nakano Y, Takinami Y, Dohi K, Nishigaki A, Takemoto H, Minagawa K, Katoh T, Willem M, Haass C, Morihara T, Tanaka T, Kudo T, Hasegawa H, Nishimura M, Sakaguchi G, Kato A, Takeda M. Itoh N, et al. Among authors: takeda m. Neurodegener Dis. 2009;6(5-6):230-9. doi: 10.1159/000236902. Epub 2009 Sep 9. Neurodegener Dis. 2009. PMID: 19738368
The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system.
Yanagida K, Okochi M, Tagami S, Nakayama T, Kodama TS, Nishitomi K, Jiang J, Mori K, Tatsumi S, Arai T, Ikeuchi T, Kasuga K, Tokuda T, Kondo M, Ikeda M, Deguchi K, Kazui H, Tanaka T, Morihara T, Hashimoto R, Kudo T, Steiner H, Haass C, Tsuchiya K, Akiyama H, Kuwano R, Takeda M. Yanagida K, et al. Among authors: takeda m. EMBO Mol Med. 2009 Jul;1(4):223-35. doi: 10.1002/emmm.200900026. EMBO Mol Med. 2009. PMID: 20049724 Free PMC article.
[Surrogate marker for ABeta42].
Okochi M, Tagami S, Yanagida K, Takeda M. Okochi M, et al. Among authors: takeda m. Nihon Shinkei Seishin Yakurigaku Zasshi. 2010 Aug;30(4):169-72. Nihon Shinkei Seishin Yakurigaku Zasshi. 2010. PMID: 20857694 Review. Japanese.
4,014 results